OBJECTIVE The Phase I dose-escalation study was conducted to evaluate the safety and pharmacokinetics of lapatinib (GW572016), a dual ErbB-1 and -2 inhibitor, in Japanese patients with solid tumors that generally express ErbB-1 and/or overexpress ErbB-2. METHODS Patients received oral lapatinib once daily until disease progression or in an event of unacceptable toxicity. RESULTS Twenty-four...

objective: the aim of the present research was to study the effect of the metacognition training on the metacognition approaches and the magnitude of disposition towards substance abuse as the result of learning various metacognition strategies.  methods: the research method was experimental with the pre-test, post-test design. the statistical population included all of abusers male in tc, by a...

the aim of this research was to investigate this research was to investigate the relationship between agricultural information system (ais) members' viewpoint towards organic products and their environmental in central district of boyer- ahmad county. the research population included researchers, extension agents and contact farmers of the study area and based on this population numbers, t...

Abstrak: Penelitian ini bermaksud mengetahui pengaruh minat baca terhadap hasil belajar bahasa Indonesia siswa di SMAN 1 Jereweh Kabupaten Sumbawa Barat, Nusa Tenggara Barat. Peneltian bertujuan untuk adanya yang signifikan antara kognitif dan psikomotorik pada mata pelajaran Indonesia. Populasi dalam penelitian adalah kelas XI sejumlah 110 siswa, sehingga sampel menjadi 86 mengikuti tabel Krej...

the purpose of this research was to study the relationship between conflict management strategies and emotional intelligence (ei) of sport coaches in east azerbaijan province. according to the statistical population of this research that consisted of all sport coaches in east azerbaijan province (n=750), 257 coaches were evaluated according to morgan table with two questionnaires including robb...

commercialization as one of the key steps in the process of innovation development transfers the findings of research and patents to market. more importantly, several factors and components influence the process of commercialization development which are necessary to be studied and identified. considering the importance of the subject, this descriptive- survey study is aimed to investigate comp...

the main purpose of this descriptive-survey study was to investigate the problems of applying cell phone in delivering agricultural consultancy, technical and engineering services. the statistical population of the study consisted of 218 experts working in agricultural consulting, technical and engineering service ventures in zanjan province. according to the kjercie and morgan table, a sample ...