نتایج جستجو برای: tuberculosis tb
تعداد نتایج: 109763 فیلتر نتایج به سال:
Cavities are important in clinical diagnosis of pulmonary tuberculosis (TB) infected by Mycobacterium tuberculosis. Although microRNAs (miRNAs) play a vital role in the regulation of inflammation, the relation between plasma miRNA and pulmonary tuberculosis with cavity remains unknown. In this study, plasma samples were derived from 89 cavitary pulmonary tuberculosis (CP-TB) patients, 89 non-ca...
Background and purpose: Several investigations recognized diabetes mellitus as one of the main risk factors for pulmonary tuberculosis (TB). This study aimed at determining the prevalence of smear-positive pulmonary TB in diabetic patients in Southwest of Iran. Materials and methods: A census study was conducted from April 2010 to December 2011 in diabetic clinic in Zahedan. Standard chest rad...
Background and purpose: Despite appropriate prevention and therapeutic activities in recent years, Pulmonary Tuberculosis (TB) is still one of the top ten causes of mortality in the world. The purpose of this study was to analyze the distribution of pulmonary tuberculosis in cities of Golestan province, Iran and identifying the major determinants of this disease. Materials and methods: from 83...
BACKGROUND The acid-fast bacillus Mycobacterium tuberculosis is often the first manifestation of acquired immunodeficiency syndrome in patients infected with human immunodeficiency virus (HIV). This study was conducted to better understand the mechanism underlying M. tuberculosis-specific pathogenicity early after onset of HIV infection. METHODS M. tuberculosis-specific T helper 1 (Th1) cells...
The emergence of multidrug-resistant tuberculosis (MDR-TB) is bringing new challenges. MDR-TB is caused by Mycobacterium tuberculosis (M. tuberculosis) that is resistant to isoniazid and rifampicin, with or without resistance to other anti-tuberculosis drugs. Approximately 450,000 people developed MDR-TB worldwide in 2012 and an estimated 170,000 people died from the disease [1] . Bacterial bur...
Definitive diagnosis of tuberculosis (TB) by conventional culture, followed by bacterial identification based on biochemical tests is time-consuming and tedious. Simple loop-mediated isothermal amplification (LAMP) specific for Mycobacterium tuberculosis complex, targeting the M. tuberculosis 16S ribosomal RNA gene, termed TB-LAMP, was evaluated as an alternative for rapid culture confirmati...
Results from DNA fingerprint analyses of Mycobacterium tuberculosis complex isolates from tuberculosis (TB) patients diagnosed during 5 years in Denmark are presented. The lack of success in eradicating TB in this low-incidence country may be explained by an unrecognized high frequency of active TB transmission (57%) among native Danes. Only two strains of M. tuberculosis are responsible for 40...
Background: Despite advances in the vaccinology and chemotherapy in the past century, tuberculosis is still responsible for two million deaths every year. Emergence of multi-drug resistant strain and coinfection of TB-HIV make it a serious concern. Treatment and control of tuberculosis is a great health burden in every community. Active tuberculosis in children has very severe consequences espe...
Background: Tuberculosis is a major cause of morbidity and mortality in Africa, especially Ghana. Despite the current treatments for tuberculosis, positive treatment outcomes are not attainable due to the differences in the socio-economic and bio-psychological status of the patients. The present study aimed to assess the influential factors in the treatment outcomes of tuberculosis. Methods: T...
BACKGROUND Tuberculosis (TB) remains the leading cause of death among human immunodeficiency virus (HIV) infected persons. The prevalence of infection with Mycobacterium tuberculosis and non-tuberculous mycobacteria (NTM) in HIV-infected patients in China is unknown. OBJECTIVE To estimate the prevalence of M. tuberculosis and NTM in HIV-infected patients in Guangxi Province, determine their d...
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