PURPOSE Intratumoral metabolic heterogeneity may increase the likelihood of treatment failure due to the presence of a subset of resistant tumor cells. Using a head and neck squamous cell carcinoma (HNSCC) xenograft model and a real-time fluorescence imaging approach, we tested the hypothesis that tumors are metabolically heterogeneous, and that tumor hypoxia alters patterns of glucose uptake w...

an evaluation of the relationship between crop yield and soil properties would be useful in estimating the fluctuations in yield, and in an implementation of correct field management. the study was conducted in farmer operated wheat fields in sorkhankalateh district, 25 km northeast of gorgan, golestan province, iran. soil samples (0-30 cm depth) were collected just after crop planting at the e...

Purpose: The cutoff values currently used to categorize tumor response to therapy are neither biologically based nor tailored for measurement reproducibility with contemporary imaging modalities. Sources and magnitudes of discordance in response assessment in metastatic colorectal cancer (mCRC) are unknown. Experimental Design: A subset of patients’ CT images of chest, abdomen, and pelvis were ...

visit-to-visit variability (vvv) in blood pressure (bp) creates challenges to hypertension control and was independent associated with increased all-cause mortality in hypertensive patients. the major goal of the present study was to investigate the association of vvv in systolic (s)bp with progression of carotid atherosclerosis and en-dothelial dysfunction in on-treated hypertensive patients.o...

abstract fluoride (f-) is an essential element for human and some animals. the fluoride concentration in irrigation water is an important index for water quality. the objective of the present study was to determine spatial variability of fluoride in groundwater and soils of some areas in arak plain. therefore, during two seasons, autumn (2007) and the end of spring (2008), 87 and 92 water sampl...

objective(s) the objective of this study was to document and explain bilateral differences in the q angle. materials and methods two hundred limbs of healthy adult indian volunteers were studied. the q angle was measured using a goniometric method with the subjects supine, quadriceps relaxed and lower limbs in neutral rotation. the relative lateral placement of the tibial tuberosity with respec...

background: antigen b (agb) is frequently used for immuno-diagnosis of hu-man cystic echinococcosis (ce). echinococcus granulosus agbs show a high degree of genetic variability in different hosts or in different ce endemic areas. the present study aimed to evaluate the genetic polymorphisms of encoding antigen b2 gene (agb2) among different iranian isolates of e. granulosus. methods: a total of...

little information is available regarding genetic variation in wild wheat relatives from iran. in this study, genetic diversity of 36 populations of wild einkorn wheat, triticum boeoticum, was studied using amplified fragment length polymorphism (aflp) primer combinations. seventeen aflp primer combinations led to amplify 979 scorable fragments ranging from 50 to 500 bp and of these, 429 (44%) ...

the pragmalinguistic and sociopragmatic aspects of language use vary across different situations, languages, and cultures. the separation of these two facets of language use can help to map out the socio-cultural norms and conventions as well as the linguistic forms and strategies that underlie the pragmatic performance of different language speakers in a variety of target language use situatio...

nitrate concentration of the soil, at the start of growing season, is high due to minerali-zation of soil organic n during the fall and the addition of n fertilizers. it may be useful to exploit this n form as much as possible. therefore, the nitrate uptake, assimilation and dry matter production of several wheat cultivars were examined in a series of experiments using a hydroponic culture syst...