The therapeutic effect of chemodynamic therapy (CDT) is significantly restricted by the stern reaction conditions and slow rate Fenton (pH 3-4). Herein, we report an ultrasmall trimetallic (Pd, Cu, Fe) alloy nanozyme (PCF-a NEs) possessing dynamic active-site synergism, thus exhibiting a cascade glutathione peroxidase (POD) mimicking activities in circumneutral pH. PCF-a NEs exhibit phototherma...

Conventional chemotherapy of pancreatic cancer (PaCa) suffers the problems of low drug permeability and inherent or acquired drug resistance. Development of new strategies for enhanced therapy still remains a great challenge. Herein, we report a new ultrasound-targeted microbubble destruction (UTMD)-promoted delivery system based on dendrimer-entrapped gold nanoparticles (Au DENPs) for co-deliv...

Abstract In this study, the synthesis of Calcium–Magnesium oxide through ball milling method using eggshell as a CaO source, developing an ecological process synthesis, is presented. After milling, annealing was carried out in order to increase crystallinity material enhance its optoelectronic properties by varying temperature from 450 900 °C. The samples were analyzed X-ray diffraction, Raman ...

Transcranial focused ultrasound technology used to transiently open the blood-brain barrier, is capable of stimulating hippocampal neurogenesis; however, it is not yet known what aspects of the treatment are necessary for enhanced neurogenesis to occur. The present study set out to determine whether the opening of blood-brain barrier, the specific pressure amplitudes of focused ultrasound, and/...

A simple and green chemical procedure was reported for the synthesis of dihydropyrimidinones from various aldehydes, ethyl acetoacetate and urea or thiourea using  holmium chloride as catalyst. The reactions were performed under solvent free conditions with ultrasound irradiation as the energy source. The advantages of this protocol include the excellent yield, operational simplicity, short tim...

PURPOSE In recent years, states have passed a range of regulations regarding ultrasound procedures in abortion care. Abortion rights opponents have promoted ultrasound viewing, believing that women who view their own ultrasound images are likely to be dissuaded from abortion. Abortion rights advocates, in contrast, routinely oppose these regulations, citing concerns that ultrasound viewing in t...