Since there are very few prospective trials in patients who undergo LVAD placement as bridge to transplantation (BTT) and very little data on the long-term use of MCS as a permanent alternative to heart transplantation (HT), or destination therapy (DT) , most of the patient selection criteria for LVAD therapy, including the criteria for DT published by the U.S. Centers for Medicare and Medicaid...

The use of ventricular assist devices (VADs) as a bridge to transplantation (BTT) has evolved considerably as clinical experience has grown and newer generation devices have become available. This study investigated the impact of VAD implantation on the clinical and economic outcomes of patients undergoing heart transplantation in the United States (US) from 2003-2007. A retrospective study was...

BACKGROUND Current ventricular assist devices (VADs) in the United States are designed primarily for adult use. Data on VADs as a bridge to transplantation in children are limited. METHODS AND RESULTS A multi-institutional, prospectively maintained database of outcomes in children after listing for heart transplantation (n=2375) was used to analyze outcomes of VAD patients (n=99, 4%) listed b...

OBJECTIVE Ventricular assist devices (VADs) have been implanted since 1990 in our institution, becoming an increasingly common treatment for end-stage heart failure. Beginning in 1997, VAD patients were discharged home when feasible. In August 2003, a dedicated multidisciplinary VAD team (cardiac surgeons, cardiologists, VAD coordinators, nurses, rehabilitation specialists, nutrition experts, p...

In this paper, we propose a robust voice activity detection (VAD) algorithm to effectively distinguish speech from non-speech in various noisy environments. The proposed VAD utilizes power spectral deviation (PSD), using Teager energy (TE) to provide a better representation of the PSD, resulting in improved decision performance for speech segments. In addition, the TE-based likelihood ratio and...

VAD, (Vincristine, Doxorubicin and Dexamethasone) was initially proposed as a salvage therapy for myeloma patients in whom prior alkylating agent therapy failed, although in recent years VAD has been surpassed by novel combination therapies with new biological agents such as thalidomide (and its derivative, lenalidomide) and bortezomib. After the excellent results obtained by the novel agents, ...

In this study, the problem of voice activity detection (VAD) is formulated in a Bayesian hypothesis testing framework. Unlike traditional VAD schemes that employ a single statistical model, multiple models are assumed to be potentially engaged with a priori probabilities, due to the statical diversity of the environmental noise degrading the speech. Moreover, the optimal a priori probabilities ...

Từ nhiều thập kỷ qua, thiếu vitamin A đang là mối quan tâm lớn về dinh dưỡng ở Việt Nam. Nghiên cứu mô tả cắt ngang tiến hành năm 2018 trên 461 học sinh nữ 11 - 13 tuổi có chỉ số Zscore chiều cao theo (HAZ) < -1, để xác định tình trạng (VAD) tại 2 huyện của tỉnh Yên Bái. Kết quả cho thấy tỷ lệ tiền lâm sàng (VAD-TLS) 5,2%, mức thấp ý nghĩa sức khỏe cộng đồng. Nhưng nguy cơ và VAD-TLS 39,9% r...

A case of invasive drug resistant thymoma, expressing P-glycoprotein, which showed noticeable clinical response to chemotherapy and the multidrug resistance modulating agents cyclosporin and quinine is reported. A 46 year old man presented with severe left shoulder pain and a diagnosis of invasive lymphoepithelial thymoma was made following chest x ray and a computed tomography scan. The patien...

The voice activity detectors (VADs) based on statistical models have shown impressive performances especially when fairly precise statistical models are employed. Moreover, the accuracy of the VAD utilizing statistical models can be significantly improved when machine-learning techniques are adopted to provide prior knowledge for speech characteristics. In the first part of this paper, we intro...