Systemic vasculitis is a group of heterogeneous diseases characterized by inflammation and blood vessel walls necrosis. Usually the skin is one of the first organs involved, especially with damage of small to medium size vessels. The cutaneous patterns may help clinicians to diagnose these diseases at the beginning of their course, preventing complications due to internal organ involvement. ...

Small vessel vasculitides such as microscopic polyangiitis and Wegener's granulomatosis commonly involve the kidney and lung, with alveolar haemorrhage being the commonest manifestation of pulmonary involvement. Here we describe a patient who developed acute renal failure and pulmonary haemorrhage with positive autoantibodies against myeloperoxidase 1 year after a diagnosis of usual interstitia...

Microscopic Polyangiitis (MPA) is an autoimmune disease characterized by pauci-immune, necrotizing, small-vessel vasculitis without clinical or pathological evidence of necrotizing granulomatous inflammation. Because many different organ systems may be involved, a wide range of symptoms are possible in MPA. Cutaneous involvement is not frequent. We describe a young girl who presented with multi...

Bleeding diathesis is a recognised complication of amyloid disease. Localised and generalised bleeding manifestations are usually associated with intravascular coagulopathy related to isolated or multiple coagulation factor deficiencies. Recently, there have been reports of haemorrhage due to amyloid deposition in blood vessel walls and in the perivascular region leading to increased fragility ...

a necessity. This is particularly true in the diabetic and the nondiabetic patient with "small vessel" or end-artery disease. Unlike occlusive disease affecting major arterial trunks, these individuals have involvement of small arteries and arterioles supplying the skin and subcutaneous tissue where development of a collateral network is at a minimum. Consequently, when injury or infection incr...

Medium-sized vessel vasculitis such as Kawasaki disease and polyarteritis nodosa (PAN) were discussed. Kawasaki disease is characterised by fever, strawberry tongue, cervical lymphadenopathy, erythema or oedema of palms and soles, and periungal desquamation in the subacute phase. Polyarteritis nodosa may be systemic or cutaneous. Symptoms and signs may include livedo reticularis, subcutaneous n...

Introduction: Takayasu Arteritis is a systemic disorder which mainly involves mediumand largesized arteries. As the disease progresses, many kinds of luminal pathology may appear, such as stenosis, occlusion and aneurysm. However, at an early stage, the vessel lumen often remains unchanged while inflammation or thickening of the vessel wall may already exist. Furthermore when the disease is act...

Background and Objective: Cerebral Arteriovenous Malformation (CAVM) hemodynamic is disease condition, results changes in the flow and pressure level in cerebral blood vessels. Measuring flow and pressure without catheter intervention along the vessel is big challenge due to vessel bifurcations/complex bifurcations in Arteriovenous Malformation patients. The vessel geometry in CAVM patients are...

In this paper, a numerical analysis of stresses and displacements in FGM thick-walled cylindrical pressure vessel under internal pressure has been presented. The elastic modulus is assumed to be varying along the longitude of the pressure vessel with an exponential function continuously. The Poisson’s ratio is assumed to be constant. Whereas most of the previous studies about FGM thick-walled p...