BACKGROUND Phytoestrogens are plant-derived natural molecules having some bone forming and bone substituting effects. In the present study, the role of phytoestrogens on bone healing was investigated in a rabbit fracture model. METHODS Twenty-two New Zealand white rabbits with right tibia fracture were divided into two groups randomly. The plant derived extract of Vitex agnus-castus L. (Verbe...

Tetranychus urticae is considered one of the main plagues in the world. Its occurrence in Pernambuco was registered for the first time in 1985 and it has caused considerable damage to the farmers, attacking different cultures of agricultural interest. The essential oils from different parts of Vitex agnus-castus harvested in the Atlantic forest in the state of Pernambuco, Brazil, were obtained ...

The benefits and costs of varying container sizes have yet to be fully evaluated to determine which container size affords the most advantageous opportunity for consumers. To determine value of the tree following transplant, clonal replicates of Vitex agnus-castus L. [Chaste Tree], Acer rubrum L. var. drummondii (Hook. & Arn. ex Nutt.) Sarg. [Drummond Red Maple], and Taxodium distichum (L.) Ric...

The aim of the present study was to evaluate the effect of a hydro-alcoholic extract of Vitex agnus-castus (VAC) fruit on blood urea nitrogen (BUN), creatinine (Cr) and, kidney histology of a female mouse model of D-galactose induced aging. In this experimental study, 72 NMRI mice were divided into 6 groups: control, VAC, D-galactose, D-galactose+VAC, aging, and aging+VAC. D-galactose was injec...

Background: For many women, the monthly suffering induced by menstrual “cramps” is severe enough to profoundly disrupt their quality of life. In the case of primary dysmenorrhea, a condition related to premenstrual syndrome (PMS), intense uterine contractions are thought to trigger moderate to intense pain despite the absence of an underlying infection or other medically-identifiable disease st...

We have demonstrated that an extract from the ripe fruit of Vitex angus-castus (Vitex), might be a promising anticancer candidate. In order to further provide a molecular rationale for clinical development in anticancer therapy, a detailed mechanism underlying the efficacy of Vitex against HL-60 cells was investigated. Vitex induced a dose- and time-dependent decrease in cell viability associat...

Objectives: 1) to determine the elasticity of normal breast tissue (parenchyma and premammary adipose tissue) in healthy women using ultrasound two-dimensional shear wave elastography (2D-SWE); 2) reveal a possible correlation between increased stiffness parenchyma hyperprolactinemia patients with mastodynia mastopathy; 3) evaluate ability Vitex agnus-castus drug reduce glandular tissue; 4) obj...

The genus Vitex, which belongs to the Verbenaceae family, includes approximately 250 species. Some species of the genus Vitex have traditionally been used for the treatment of headaches, ophthalmodynia, coughs, asthma, premenopausal syndrome, etc. Chemical investigations indicate that the characteristic constituents of the genus Vitex are terpenes, and 210 of these compounds, including monoterp...