Glomerular filtration rate (GFR) is the gold standard in kidney function assessment and is used to determine progression of kidney disease and drug-induced kidney toxicity. One of the most accepted ways to assess GFR is by measuring the rate of disappearance of labeled inulin from the blood; as inulin is completely filtered at the kidneys’ glomeruli (but neither secreted nor reabsorbed by the t...

GFR markers Among newer GFR markers in ARF, serum cystatin C deserves evaluation since it has been shown more sensitive and accurate than serum creatinine in several settings, but has not been validated as a GFR indicator in ARF (1-2). Another endogenous marker, β2-microglobulin, has been suggested as a GFR estimate (3). Measuring tubular enzymuria could facilitate the early detection of renal ...

OBJECTIVE: Diabetic nephropathy is a major diabetes complication. Arterial resistance index (RI) may predict deterioration in kidney function. This study was designed to compare renal arterial RI in different stages of renal function according to glomerular filtration rate (GFR), serum creatinine level and proteinuria. MATERIALS AND METHODS: In a cross-sectional study on 81 diabetic patients i...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background: definitions of chronic kidney disease (ckd) in many catheterization laboratories have relied on the serum creatinine (scr) rather than glomerular filtration rate (gfr). regarding that ckd is the primary predisposing factor for contrast induced nephropathy (cin), we compared the sensitivity of calculated gfr by ...

The clinical usefulness of the quantity height (cm)/plasma creatinine (Ht/Pcr) as a predictor of glomerular filtration rate (GFR) was investigated in 163 children with varying levels of renal function. Plasma creatinine levels (mumol/l) were measured by an automated reaction rate method. The results indicate that in rather more than half the children studied, an estimate of GFR adequate for ord...