background: preterm labor (ptl) is one of the most important causes in neonatal mortality and morbidity. late preterm labor (34-36w) includes 75% of such birth. assisted reproductive technology (art) pregnant women are at increased risk of ptl. objective: the study has been undertaken to determine whether beginning and continuing 17-α hydroxy progesterone caproate can reduce risk of ptl or chan...

A series of 3-styrylchromone derivatives (4-20) were synthesized and the structure-activity relationships for α-glucosidase inhibition and antioxidant activities were analyzed. Among the synthesized compounds, compounds 15 and 20, which contain a catechol moiety, showed both potent 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity (15: EC₅₀=17 µM; 20: EC₅₀=23 µM) and α-gluco...

We present quenched results for B meson decay constants using NRQCD b quarks and O(a) tadpole improved clover light quarks. For the first time, one-loop matching factors between lattice and continuum currents are incorporated through O(α/M) taking operator mixing fully into account. This includes an important O(α a) discretization correction to the heavy-light axial vector current. We find f B ...

We describe the GIT quotient of the linear system of (3, 3) curves on P × P as the final non-trivial log canonical model of M4, isomorphic to M4(α) for 8/17 < α ≤ 29/60. We describe singular curves parameterized by M4(29/60), and show that the rational map M4 99K M4(29/60) contracts the Petri divisor, in addition to the boundary divisors ∆1 and ∆2. This answers a question of Farkas.

Development of immunoprotection against visceral leishmaniasis (VL) focused on the identification of antigens capable of inducing a Th1 immune response. Alternatively, antigens targeting the CD8 and T-regulatory responses are also relevant in VL pathogenesis and worthy of being included in a preventive human vaccine. We assessed in active and cured patients and VL asymptomatic subjects the clin...

The adsorption properties and mechanics of selected endocrine disrupting compounds; 17 β-estradiol, 17 α – ethinylestradiol and bisphenol A on locally available black tea leaves waste and granular activated carbon were investigated. The results obtained indicated that the kinetics of adsorption were pH, adsorbent dose, contact time and temperature dependent with equilibrium being reached at 20 ...

A sterically demanding unsymmetrical pentafluorophenyl-triisopropylphenyl-λ(3)-iodane was developed as an effective reagent for the electrophilic pentafluorophenylation of various β-keto esters and a β-keto amide. 17 examples of α-pentafluorophenylated 1,3-dicarbonyl compounds 3 having a quaternary carbon center are provided. The resulting compounds were nicely transformed into chiral α-pentafl...

INTRODUCTION Interferon alpha (IFN-α) has a complex role in autoimmunity, in that it may both enhance and prevent inflammation. We have previously shown that the presence of IFN-α at sensitization protects against subsequent antigen-triggered arthritis. To understand this tolerogenic mechanism, we performed a descriptive, hypothesis-generating study of cellular and humoral responses associated ...

BACKGROUND Recent studies have discovered that α-globin is expressed in blood vessel walls where it plays a role in regulating vascular tone. We tested the hypothesis that blood pressure (BP) might differ between normal individuals and those with α+thalassemia, in whom the production of α-globin is reduced. METHODS AND RESULTS The study was conducted in Nairobi, Kenya, among 938 adolescents a...

Background: Given the variations in clinical presentation and physiopathological mechanisms in irritable bowel syndrome (IBS) subtypes, it is an acknowledged fact that the response to treatments can be disparate. Objective: To assess the effect of vitamin D on inflammatory cytokines (IL-17, IL-10, TNF-α), and biomarkers of oxidative stress (total antioxidant capacity (TAC), and malondialdehyde ...