A novel method of fabricating water-soluble bio-probes with ultra-small size such as NaYF4:Yb,Er (18 nm), NaGdF4:Yb,Er (8 nm), CaF2:Yb,Er (10 nm), PbS (7 nm), and ZnS (12 nm) has been developed to provide for the solubility switch of nanoparticles from oil-soluble to water-soluble in terms of hydrion rivalry aided by ultrasonic. Using NaYF4:Yb,Er (18 nm) as an example, we evaluate the propertie...

The present work includes synthesis of new series heterocyclic derivatives containing 6-amino-1,3-dimethyl uracil moiety linked to 1,2,4-triazole [6-8 and 10]. first way reaction 6-amino-1,3-dimethyluracil with ethyl chloroacetate K2CO3 as catalyst in DMF solvent gives ester derivative [1]. Then, compound [1] was converted into (semicarbazide, thiosemicarbazide, phenylsemicarbazide hydrazide de...

يتضمن البحث تحضيرحامض الاثيلين ثنائي الامين رباعي حامض الخليك اللامائي [ 1] من خلال تفاعلمع (ethylene diamine tetraacetic acid) EDTA مادة الخليكحامض وبوجود البيريدين تحت ظروف التصعيد.في الخطوة الثانية التحضير العضوي تم مفاعلة المركب مع الكحول الحاوي على حلقة غير متجانسةليتكون استرالخلات الثنائي 2] في تركيبه مجموعة الاستر tetrahydrofurfuryl alcoholوالحلقة المتجانسة بشكل ثنائي.تم تنقية المركبات ا...

metabonomics and other “omics” fields are essential science in analytical chemistry. modern analytical instruments such as proton nuclear magnetic resonance ( 1 h nmr) can be provided the great quantity of analytical information. in order to assign unknown samples, chemometrics methods recognition build classification model based on experimental data.  firstly some current strategies for regard...

In this study, a class of bis-1,2-(4-aryl-2-alkyl-1H- inden-1-yl) ethane was synthesized and characterized by spectroscopic methods such as 1HNMR, 13CNMR, melting point and FTIR. bis-1,2-(4-aryl-2-alkyl-1H- inden-1-yl) ethane was synthesized by the reaction of butyl­lithium, arylindenes and dibromoethane in a facile, one-pot strategy. It’s shown that these methods have a wide scope to afford li...

Some new 3-[(5-benzylidene-2-phenyl)-3, 5-dihydro-4-H-imidazol-4-one-3-(4-bezoylhydrazono)]-indole-2-ones (VIII) have been synthesized from different isatinhydrazones (II) by condensing with 2-phenyl-5-benzylidene- 3-N (4-acetyl phenyl)-1, 5-dihydro-imidazol-4-one (VII). Their chemical structures have been confirmed by IR, 1HNMR, MASS and by elemental analysis. Investigation of antimicrobial ac...

A series of monoazo disperse dyes based on naphthalimide was synthesized using N-alkylcarboxylic acid-1,8-naphthalimide as diazo component and N,N-diethylaniline derivatives as a coupling components. 4-amino-N-ethanoic (propanoic) acid-1,8-naphthalimide was synthesized from 4-nitro-1,8-naphthalic anhydride by imidation and subsequent reduction reactions. These compounds were diazotized and furt...

An  efficient  three-component  one-pot  synthesis  of 1-amidoalkyl-2-naphthols  from  2-naphthol, aldehydes, and acetamide using nano-SnO2as catalyst is described. The reactions were carried out at 80oC under water-solvent media. The structures of the compounds were characterized by IR, 1HNMR, 13C-NMR,  and  Mass  spectra  and  by  elemental  analysis.  The  advantages  of  the  effective meth...

Colorectal cancer (CRC) is a growing cause of mortality in developing countries, warranting investigation into its earlier detection for optimal disease management. A metabolomics based approach provides potential for noninvasive identification of biomarkers of colorectal carcinogenesis, as well as dissection of molecular pathways of pathophysiological conditions. Here, proton nuclear magnetic ...

The potential of marine crabs as a source of biologically active products is largely unexplored. In the present study, antimicrobial activity of the hemolymph (plasma) and hemocytes (plasma cells) of six brachyuran crabs was investigated against 16 pathogenic strains. Among the 16 strains tested maximum zone of inhibition was recorded in the hemolymph of Hyas araneus against Shigella flexineri....