1 Amado RG, Wolf M, Peeters M, et al. Wild-type KRAS is required for panitumumab effi cacy in patients with metastatic colorectal cancer. J Clin Oncol 2008; 26: 1626–34. 2 Van Cutsem E, Kohne CH, Hitre E, et al. Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer. N Engl J Med 2009; 360: 1408–17. 3 De Roock W, Claes B, Bernasconi D, et al. Eff ects of KRAS, BRAF, NR...

The flood hazard in New York City depends on both storm surges and rising sea levels. We combine modeled storm surges with probabilistic sea-level rise projections to assess future coastal inundation in New York City from the preindustrial era through 2300 CE. The storm surges are derived from large sets of synthetic tropical cyclones, downscaled from RCP8.5 simulations from three CMIP5 models....

objectives:  to identify the predictive factors of successful non-operative management of patients with intraperitoneal bleeding following blunt abdominal trauma. methods:  this was cross-sectional study being performed in our level i trauma center in southern iran between 2010 and 2011. we included adult (>14 years) patients with blunt abdominal trauma and intraperitoneal hemorrhage detected b...

This study continues a long history of author co-citation analysis (and, more recently, author bibliographic coupling analysis) of the intellectual structure of information science (IS) into the time period of 2006-2010. It finds that Web technologies continue to drive developments, especially for the research front, although perhaps more indirectly than before. A broadening of perspectives is ...

1 Universidad Autónoma del Carmen, Avenida 56 No. 4, Esq. Av. Concordia, Col. Benito Juarez, 24180 Ciudad del Carmen, CAM, Mexico 2 Benemérita Universidad Autónoma de Puebla, Facultad de Ciencias de la Computación, Ciudad Universitaria, 14 sur y Avenida san Claudio, Edificio 104C, Colonia San Manuel, 72570 Puebla, PUE, Mexico 3 Universidad Autónoma del Estado de Hidalgo, Av Universidad S/N, Cen...

The underground economy has long been of interest to economists and has devoted extensive studies to itself in economic literature. Through fuzzy logic approach in present research, we estimated the size of underground economy of Iran over the period of 1978-2010. For this purpose and according to theoretical bases and previous studies, variables such as GDP per capita, ratio of direct taxes to...

In the present study, ten steel-moment resisting frames (SMRFs) having different numbers of stories ranging from 3 to 20 stories and fundamental periods of vibration ranging from 0.3 to 3.0 second were optimized subjected to a set of earthquake ground motions using the concept of uniform damage distribution along the height of the structures. Based on the step-by-step optimization algorithm dev...

T elimination of health disparities in the United States is a national priority and overriding goal for Healthy People 2010 (HP 2010). Surveillance of health indicators among minority populations is essential to eliminating disparities. Surveillance is critical for program planning, policy making, evaluating population-based strategies, and tracking progress toward national and state objectives.