Both gastrin and Helicobacter pylori have been shown capable of up-regulating gene expression and protein shedding of heparin-binding epidermal growth factor (HB-EGF). Furthermore, the bacteria have previously been shown to induce serum hypergastrinemia in infected individuals. The aim of this work was to assess the extent to which the ability of H. pylori to upregulate expression of HB-EGF can...

BACKGROUND The aim of this study was to examine the effect of anxiety about falling on selected physiological parameters on the lead (LC) and top-rope climbing (TRC) methods. For this purpose the physical differences between the two methods have been eliminated and the effect of only the anxiety about falling on the physiological parameters has been studied. METHODS A total of 26 intermediate...

The famous 2R hypothesis was first proposed by Susumu Ohno in 1970. It states that the two whole genome duplications had shaped the genome of early vertebrates. The most convincing evidence for 2R hypothesis comes from the 4:1 ratio chromosomal regions that have preserved both gene content and order in vertebrates compared with closely related. However, due to the shortage of such strict eviden...

Enantiomers (2S, 4S)- and (2R, 4R)-3-(naphthalene-1-ylmethyl) pentane-2,4-diols were synthesized by the reduction of (Z)-4-hydroxy-3-(naphthalene-1-ylmethyl) pent-3-en-2-one with NaBH4 in methanol (MeOH). Crystallization dichloromethane this racemic mixture led to simple crystals a crystalline habit similar morphologies; however, group them, it was possible find barely observable difference tha...

Substitution effects are probed for novel N-heterocyclic stannylenes (NHSns), including 1,4-di(R)-tetrazole-5-stannylenes (1R), and 1,3-di(R)-tetrazole-5-stannylenes (2R), using B3LYP/6-311++G** level of theory. Nucleophilicity, multiplicity, and stability of 1R and 2R are calculated; with R = H, methyl, ethyl, i-propyl, t-butyl, Ph, OH, methoxy, NO2, CN and CF3. Asymmetric 2H appears more nucl...

The function decomposition problem can be stated as: Given the algebraic expression of the composition of two mappings, how can we identify the two factors? This problem is believed to be in general intractable [1]. Based on this belief, J. Patarin and L. Goubin designed a new family of candidates for public key cryptography, the so called \2R schemes" [10, 11]. The public key of a \2R"-scheme ...

BACKGROUND Epstein-Barr virus (EBV) infection in infectious mononucleosis (IM) is associated with lymphocyte activation leading to the expansion of cells expressing activation-associated antigens. Most of these antigens are released as soluble molecules in vitro and in vivo. METHODS We investigated the serum levels of the soluble forms of the CD8 (sCD8), p55-IL-2R alpha (sIL-2R alpha), and CD...