A549 xenografts were allowed to grow in nude mice to about 5 mm in diameter, then diets were changed to modified AIN-76 diets containing 19% wt./wt. fish oil (FO) or 20% wt./wt. corn oil (CO). Ten days later dietary ferric citrate (0.3% wt./dry wt.) was added and doxoribicin (DOX) treatment (3.6 mg/kg i.v. each of the 5 days for 18 days) commenced. Treatment with DOX halted the growth of tumors...

from 1996 to 2002, fifty three patients with major beta-thalassemia received allogeneic peripheral blood stem cell trans plantation (pbsct). median age was 6 years .twenty two were class i, 17 class ii and 14 class iii. all of the donors were hla-identical. conditioning regimen for class i and ii patients consisted of cyclophosphamide (cy) 50 mg/kg/day for 4 days + busulfan (bu) 3.5 mg/kg for 4...

A water-soluble nitrosourea, 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-1-(2-chloroethyl)-1-nitrosourea hydrochloride (ACNU), was tested for antitumor activity against lymphoid leukemia L-1210 in BDF1 mice. The results obtained were as follows: (1) ip--ip system: By daily administrations optimal dose for 12 days, MED (ILS40), and therapeutic ratio were found to be 18 mg/kg, 1.3 mg/kg, and 14, r...

persian oak (quercus brantii lindl., the fagaceae family) is a medicinal plant which seed flour is used to treat inflammatory and gastric ulcers by the tribes in southwestern iran. the current study was done to evaluate the effect of hydro-alcoholic extract of q. brantii seed flour for treatment of gastric ulcers induced by ethanol in wistar rats. the hydro-alcoholic extract of q. brantii was t...

Adequate fluid resuscitation in adults with major burns is crucial to prevent or minimize burn shock, but needs be balanced against the complications of over-resuscitation. A single-center, retrospective review 95 ICU patients severe from Jan 2014 Aug 2021 was performed. Some 52 were managed a liberal targeted goal 4 mL/kg/%TBSA, and 43 after we incorporated restricted 2 mL/kg/%TBSA into our st...

The objective of this inquiry was to know the impact pooled soccer, plyometric, and sprint drill on speed agility among underweight males. 26 male subjects were chosen with a BMI (kg/m2) less than 18.5. ages ranged from 18-22 years. physical fitness tests administered before after training program 20m sprint, 40m agility. plan engaged for six weeks, 45M per exercise phase, two days week. combin...

Background: According to several reports there is a positive correlation between the lowered quality of semen and any exposure to toxic compound specially those particularly disrupt endocrine functions. Like other herbicides atrazine (ATR) induces endocrine disruption and consequently interferes with sexual hormones physiological functions. Therefore current study was designed in order to evalu...