The cost of attending college has been steadily rising and in 10 years is estimated to reach $140,000 for a 4-year public university. Recent surveys estimate just over half of US families are saving for college. State-operated 529 college savings plans are an effective way for families to plan and save for future college costs, but only 3% of families currently use them. The Office of the Illin...

Range sensors are devices that capture the threedimensional (3-D) structure of the world from the viewpoint of the sensor, usually measuring the depth to the nearest surfaces. These measurements could be at a single point, across a scanning plane, or a full image with depth measurements at every point. The benefits of this range data is that a robot can be reasonably certain where the real worl...

Outside-in integrin alphaIIbbeta3 signaling is required for normal platelet thrombus formation and is triggered by c-Src activation through an unknown mechanism. In this study, we demonstrate an essential role for protein-tyrosine phosphatase (PTP)-1B in this process. In resting platelets, c-Src forms a complex with alphaIIbbeta3 and Csk, which phosphorylates c-Src tyrosine 529 to maintain c-Sr...

Fibrinogen binding to activated integrin induces outside-in signaling that results in stable platelet aggregates and clot retraction. How integrin αIIbβ3 is discouraged from spontaneous activation is not known. We have recently shown that junctional adhesion molecule-A (JAM-A) renders protection from thrombosis by suppressing integrin outside-in signaling. In this study, we show that JAM-A asso...

BACKGROUND Toxoplasmosis is a life-threatening infection in organ transplant recipients, people receiving corticosteroid or radiation therapy, people with malignancies, and AIDS patients. OBJECTIVES The current study aimed to determine the prevalence of toxoplasmosis in patients receiving chemotherapy for malignancies in the Bushehr province of southwest Iran. METHODS Blood samples were tak...

PURPOSE To evaluate the urological journal publication productivity of Japanese urologists based on their physician years. METHODS All original articles written by Japanese urologists and published from Japanese institutions in 6 primary urological journals between 2010 and 2014 were reviewed (N = 529 articles). RESULTS The median post-graduate years of the first and corresponding authors o...

Cobalamin-independent methionine synthase (MetE) catalyzes the synthesis of methionine by a direct transfer of the methyl group of N5-methyltetrahydrofolate (CH3-H2PteGlun) to the sulfur atom of homocysteine (Hcy). We report here the first crystal structure of this metalloenzyme under different forms, free or complexed with the Hcy and folate substrates. The Arabidopsis thaliana MetE (AtMetE) c...

CONTEXT Impaired postural control in single-limb stance and aberrant drop-landing mechanics have been implicated separately as risk factors for noncontact anterior cruciate ligament (ACL) injury, but associations between these variables has not been reported. OBJECTIVE To determine whether there are associations between single-limb postural control and drop-landing mechanics. SETTING Univer...

BACKGROUND AND PURPOSE Elastase-induced aneurysms in rabbits have been proposed as a useful preclinical tool for device development. The object of this study was to report rates of morbidity and mortality associated with the creation and embolization of elastase-induced rabbit aneurysms and to assess the impact of operator experience on these rates. MATERIALS AND METHODS Elastase-induced mode...