A quantitative approach is presented to evaluate fatty acid incorporation in fish. Fatty acid composition of European sea bass juvenile was studied during an experiment using 6 isoproteic (54%) and isolipidic (18%) diets containing 0.23, 0.56, 0.72, 0.86, 1.01 and 1.86% DM n-3 highly unsaturated fatty acids (n-3 HUFA). Whole body fatty acid compositions were studied at the beginning and after 5...

A highly sensitive method to determine agonist-induced release of endogenous fatty acids from cells in culture was developed using high-performance liquid chromatography and fluorescence detection. Fatty acids were selectively derivatized with 1-pyrenyldiazomethane and separated on a LC18 reversed phase column using an acetonitrile-water gradient. The detection limit was approx. 20 fmol and the...

Metabolic endotoxemia, commonly derived from gut dysbiosis, is a primary cause of chronic low grade inflammation that underlies many chronic diseases. Here we show that mice fed a diet high in omega-6 fatty acids exhibit higher levels of metabolic endotoxemia and systemic low-grade inflammation, while transgenic conversion of tissue omega-6 to omega-3 fatty acids dramatically reduces endotoxemi...

introduction regular intake of n-3 fatty acids of marine origin have desirable effects on serum lipoproteins and reduce coronary vascular disease (cvd). n-3 fatty acid supplementation decreased serum triglyceride concentrations in studies in which most of the subjects were male. the effects of n-3 fatty acids supplementation in fat women especially postmenopausal fat women have received little ...

Background Previous studies have reported inconsistent findings regarding the efficacy of omega-3 fatty acids on pregnant women with major depressive disorder (MDD). This meta-analysis was conducted to systematically evaluate the clinical applicability of omega-3 fatty acids in treating depression in pregnant women. Methods Randomized controlled trials (RCTs) that compared omega-3 fatty acids ...

background: application of different sources of fatty acids and their effect on ovarian performance is a current issue in animal science and research centers. objectives: the purpose of this study was to determine the effect of different fatty acids in close-up period on population and size of follicles and measuring blood parameters related to the energy state of the body after calving of lact...

Leptin directly increases the rate of exogenous glucose and fatty acids oxidation in isolated adipocytes. However, the effects of leptin on fatty acid metabolism in white adipose tIssue have not been examined in detail. Here, we report that in adipocytes incubated for 6 h in the presence of leptin (10 ng/ml), the insulin-stimulated de novo fatty acid synthesis was inhibited by 36% (P<0.05), whi...

A high intake of saturated fatty acids and cholesterol is associated with a high incidence of occlusive arterial lesions involving both atherosclerosis and thrombosis. The evidence is based on epidemiological, experimental, and clinical studies. Such dietary habits increase serum low density lipoprotein cholesterol, a main risk factor for atherosclerosis. The mechanisms by which dietary saturat...

A high Intake of saturated fatty acids and cholesterol Is associated with a high Incidence of occluslve arterial lesions Involving both atherosclerosis and thrombosis. The evidence Is based on epidemiological, experimental, and clinical studies. Such dietary habits Increase serum low density llpoproteln cholesterol, a main risk factor for atherosclerosis. The mechanisms by which dietary saturat...