Facebook’s experimental manipulation of newsfeed content and the subsequent PNAS publication of significant findings from it (1) have drawn attention to the regulation of human participation in academic research and to the differences between commercial and academic research. Those events were recognized in an Expression of Concern in PNAS (2). In commerce and on the Internet, experimentation i...

BACKGROUND AND PURPOSE We determined the relationship between apolipoprotein (Apo)E, MRI, and low cognitive scores. METHODS The relationship between age, education, ApoE genotype, MRI examination of the brain, subclinical and clinical cardiovascular disease, and low (<80) score on the Modified Mini-Mental State Examination (3MSE, as modified by Teng and Chui) was evaluated for 3469 black and ...

The purpose of this research is to examine the meaning life in young adults, middle adults and advanced during COVID-19 pandemic. study group consists 620 403 female (65%) 217 male (35%) residing various provinces Turkey. age range participants ranged from 20 80 (x̄=37.8), with 383 (61.78%) adulthood, 134 (21.61%) adulthood 103 (16.61%) adulthood. Explanatory sequential design, one mixed methods...

INTRODUCTION Globally, increasing numbers of HIV-infected children are reaching adolescence due to antiretroviral therapy (ART). We investigated rates of loss-to-follow-up (LTFU) from HIV care services among children as they transition from childhood through adolescence. METHODS Individuals aged 5-19 years initiated on ART in a public-sector HIV clinic in Bulawayo, Zimbabwe, between 2005 and ...

OBJECTIVES Commercial trainable hearing aids (HA) (i.e., devices that for a period are adjusted by the user in different acoustic environments and that subsequently with changing environments automatically adapt to the user's preferred settings), are readily available; however, little information exists about the efficacy of training a HA. The purpose of this study was to investigate the effica...

Methods Eighty participants (57.5% female, mean age 70 years) were recruited from local podiatry clinics and The University of Newcastle. Automated Systoe (Atys Medical) and MicroLife (BP A100 Plus) devices were used to measure toe and brachial systolic blood pressures respectively, after 5, 10, and 15 minutes of rest. Two Podiatrists measured 20 participants on the same day to establish inter-...

OBJECTIVES To determine whether the attitudes to sexual and reproductive health of a cohort of university students had changed from 2005 to 2013. METHODS Questionnaires (1,000) on sexual and reproductive health attitudes were randomly distributed to students at Shanghai Jiaotong University in May 2013. All participants volunteered for the study and their answers were anonymous. The questionna...

We assessed the association between several cardiometabolic risk factors (CRFs) (blood pressure, LDL-cholesterol, HDL-cholesterol, triglycerides, uric acid, and glucose) in 390 young adults aged 19-20 years in Seychelles (Indian Ocean, Africa) and body mass index (BMI) measured either at the same time (cross-sectional analysis) or at the age of 12-15 years (longitudinal analysis). BMI tracked m...

DESIGN, SETTING, AND PARTICIPANTS Weobserved the Age-Related Eye Disease Study (AREDS) participants for an additional 5 years after a randomized clinical trial of antioxidant vitamins andminerals was completed. Observation occurred at 11 clinical sites of medical retinal practices from academic institutions and community medical centers. Participants aged 55 to 80 years with no AMD or AMD of va...