The appearance of cataracts in animals with experimental diabetes has been described in dogs with pituitary6 or pancreatic diabetes,"'3 in rats with pancreatic,3'9 alloxan1"'11 or dehydro-ascorbic acid diabetes,' and in alloxan diabetic rabbits."'7 According to some of these investigators"1', the app,earance of cataracts is correlated with the degree of hyperglycemia and glycosuria. The observa...

The objective of this paper was to study the therapeutic effect of Stigma maydis polysaccharides in diabetic mice. Mouse models of types 1 and 2 diabetes were established. The body weight, food intake, water intake as well as blood sugar level and glucose tolerance of mice were measured. Stigma maydis polysaccharides can improve the symptoms of weight loss and polydipsia in diabetic mice, and h...

PURPOSE To evaluate the effect of diabetes mellitus and of sildenafil citrate on female urethral function. METHODS Twenty nine female rats were divided into four groups: G1 - (n=9), normal rats; G2 - (n=6), normal rats treated with sildenafil citrate; G3 - (n=9) rats with alloxan-induced diabetes; G4 - (n=5) rats with alloxan-induced diabetes treated with sildenafil citrate. Under anesthesia,...

Materials and methods There were 4 groups (G): G1 (non-pregnant controls rats), females that received intraperitoneal injection (ipi) of 0.9% saline (s), G2 (non-pregnant diabetic rats), females that received ipi of alloxan (100 mg/kg) diluted in 0.9% s, G3 (control mothers), mothers that received ipi of 0.9% s and G4 (diabetic mothers), mothers that received ipi of alloxan (100 mg/kg) diluted ...

Xylitol is a polyalcohol which is a regular intermediary product of the carbohydrate metabolism.1 Although there have been many reports on the effects of xylitol on the carbohydrate metabolism in animals and human beings,2,3 there have been few published data on the metabolic changes induced by the adminis tration of xylitol in acute and subacute liver injury. Accordingly, studies were undertak...

background: the effects of aqueous extract of fadogia agrestis stem at the doses of 18, 36, and 72 mg/kg body weight on alloxan-induced toxicity was investigated in wistar rats. methods: in total, 35 rats of both sexes (132.80±7.22g) were randomized into five groups (a-e): animals in group a received 0.5 ml of distilled water orally on daily basis for 15 days while the alloxanized rats in group...

introduction: diabetes mellitus is a metabolic disorder of the endocrine system leading to increased blood glucose concentration in the patients. as a basic treatment for managing the blood glucose level, insulin or hypoglycemic medications are used but herbal medicines are more favored. the design of this research project was to study the therapeutic effect of hydroalcoholic extract of melissa...

background: combinatorial effects of aqueous root extract of jatropha curcas (jc) and j. gossypiifolia (jg) in alloxan-induced diabetic rats was investigated in this research. methods: thirty-six wistar rats were randomized into six groups of six animals each. group i (control) was not induced but received 0.5 ml of distilled water. groups ii, iii, iv, v and vi were induced with diabetes mellit...

background: the effects of aqueous extract of fadogia agrestis stem at the doses of 18, 36, and 72 mg/kg body weight on alloxan-induced toxicity was investigated in wistar rats. methods: in total, 35 rats of both sexes (132.80±7.22g) were randomized into five groups (a-e): animals in group a received 0.5 ml of distilled water orally on daily basis for 15 days while the alloxanized rats in group...

background: saffron is the dried stigmata of the flowers of saffron (crocus sativus l., iridaceae). saffron and its major active constituents, crocin (crocetin glycoside), crocetin and safranal, have a variety of pharmacological effects including high antioxidant properties and crocetin has insulin sensitizing effect possibly due to its antioxidant activity. oral crocin is not absorbed and is h...