Abstract Study question Is there an advantage for modified flare/ GnRH antagonist protocol in comparison to oocyte cryopreservation cycles? Summary answer Modified is at least as good cycles, potentially improving maturity rate subgroup of patients. What known already Ultrashort flare agonist (GnRHa)/GnRH -antagonist offer benefits stimulatory effect repeated microdose on endogenous FSH and the...

Two experiments were conducted to determine whether administering a dopamine antagonist to steers fed endophyte-infected (E+) tall fescue would increase serum prolactin (PRL) and reduce rectal temperature. Steers in both experiments were housed in environmentally controlled chambers (32 degrees C; 50% relative humidity). In Exp. 1, 10 steers were allotted randomly to receive s.c. injections of ...

background: microdose flare-up gnrh agonist and gnrh antagonist have become more popular in the management of poor ovarian responders (por) in recent years; however, the optimal protocol for por patients undergoing in vitro fertilization has still been a challenge. methods: in this observational study design, two hundred forty four poor ovarian responders were retrospectively evaluated for thei...

Complement C5a is a potent inflammatory chemoattractant and might be beneficial therapeutic target for the induction of an effective anti-tumour response. agonist antagonist modulation have been demonstrated to either promote or inhibit tumour development in EMT6 murine mammary cancer cells both vitro vivo studies. For studies Alamar Blue cell viability assay was used determination, immunofluor...

Introduction: Natalizumab is an integrin receptor antagonist that has been approved by the Food and Drug Administration to treat multiple sclerosis Crohn’s disease. The drug linked increased risk of melanoma. This brief report highlights innovative clinical approach for monitoring skin patients prescribed natalizumab.

Diabetic neuropathic pain, an important micro vascular complication in diabetes mellitus, has been recognized as one of the most difficult types of pain to treat. Lack of understanding of etiology involved, inadequate relief, development of tolerance and potential toxicity of classical anti-nociceptive agents warrants the investigation of newer agents to relieve this pain. The aim of the presen...

Introduction: Feverfew (Tanacetum parthenium) (T.p.) is widely used in folk medicine to treat many diseases. We reported the analgesic effect of T.p. flower and leaf previously. Present study is designed to find the mechanism underlying the anti-nociceptive effect of the aqueous extract of T.p. flower. Method: Based on our previous study, the dose 50 mg/kg i.p. of the T.p. aqueous extract had...

Glucagon and the glucagon receptor are most important molecules control over blood glucose concentrations. These two molecules are very important to studies of type 2 diabetic patients. In literature, several classes of small molecule antagonists of the human glucagon receptor have been reported. Glucagon receptor antagonist could decrease hepatic glucose output and improve glucose control in d...

Background: Male factors, mainly spermatogenesis disorder, are responsible for 20-30% of infertility occurs in different societies. One of the known causes of spermatogenesis disorder is chemotherapy in patients with cancer. The side effect of chemoterpic agents may last from 10 years up to the end of the life. Since dividing cells are mainly affected by anticancer drugs, the aim of the present...