OBJECTIVES DMBT is an antibacterial pattern recognition and scavenger receptor. In this study, we analyzed the role of DMBT1 single nucleotide polymorphisms (SNPs) regarding inflammatory bowel disease (IBD) susceptibility and examined their functional impact on transcription factor binding and downstream gene expression. METHODS Seven SNPs in the DMBT1 gene region were analyzed in 2073 indivi...

Objective(s) Rapidly growing mycobacteria (RGM) are capable of producing diseases in humans. Since mycobacteria vary in their susceptibility, precise identification is critical for adoption of correct drug therapy. The main aim of this study was molecular identification and evaluation of antimicrobial susceptibility pattern of Iranian clinically isolated Myocbacterium fortuitum. Materials and...

BACKGROUND & OBJECTIVES As a result of immune defects in Sickle cell disease (SCD), affected individuals are prone to infection from encapsulated bacterial pathogens like Streptococcus Pneumoniae. Studies on the etiological agents of bacteremia in children with SCD in Nigeria are few and have revealed a spectrum of organisms that is different from those recorded in other parts of the world. A...

Recent global concern is that the inappropriate treatment and misuse of antibiotics leads to the emergence of antibacterial multidrug resistance in Proteus vulgaris and others common pathogenic bacteria. The present study investigates the prevalence of antibiotic resistance among Proteus vulgaris bacterial isolates from urine samples of UTI infected hospitalized patients. Thirty six (36) strain...

Background and Aim: This research aims to study the qualitative melissopalynology analysis, Glucose oxydase (GOX) activity, and the antibacterial effect of honey samples from different botanical and geographical origins. Materials and Methods: Five natural honey samples were collected from local beekeepers. The antibacterial effect was carried out towards pathogenic bacteria including Escheric...

Disk diffusion is one method of susceptibility testing of the Mycobacterium fortuitum complex to antibacterial agents. We utilized disks of polymyxin B (300 U), amikacin, and kanamycin to determine whether they could also be used for species identification when compared with standard biochemical methods. With the polymyxin disk, 100% of 75 M. fortuitum strains produced zones of inhibition, wher...

The eusocial honey bee, Apis mellifera, has evolved remarkable abilities to survive extreme seasonal differences in temperature and availability of resources by dividing the worker caste into two groups that differ in physiology and lifespan: summer and winter bees. Most of the recent major losses of managed honey bee colonies occur during the winter, suggesting that winter bees may have compro...

BACKGROUND Sheep constitute the second major component of livestock in Ethiopia. However, efficient utilization of this potential resource is hampered by combination of health problems, poor management and feed shortage. Haramaya district is one of the remote settings in Ethiopia where information about the livestock disease is not well documented. Hence this study was conducted to determine th...