nowadays, we live in a world which quality, speed, accuracy and cost are the most important parameters in parts' design and manufacturing. due to the complexity of part manufacturing, traditional and nontraditional manufacturing techniques are used. aerodynamic tests usually requires one or several models for testing in wind tunnels and these models typically have particular complexities in whi...

In conventional multi-armed bandits (MAB) and other reinforcement learning methods, the learner sequentially chooses actions and obtains a reward (which can be possibly missing, delayed or erroneous) after each taken action. This reward is then used by the learner to improve its future decisions. However, in numerous applications, ranging from personalized patient treatment to personalized web-...

In this note we prove a tight lower bound for the MNL-bandit assortment selection model that matches the upper bound given in (Agrawal et al., 2016a,b) for all parameters, up to logarithmic factors.

We consider the shortest path routing (SPR) of a network with stochastically time varying link metrics under potential adversarial attacks. Due to potential denial of service attacks, the distributions of link states could be stochastic (benign) or adversarial at different temporal and spatial locations. Without any a priori, designing an adaptive SPR protocol to cope with all possible situatio...

Modern conflict-driven clause-learning SAT solvers routinely solve large real-world instances with millions of clauses and variables in them. Their success crucially depends on effective branching heuristics. In this paper, we propose a new branching heuristic inspired by the exponential recency weighted average algorithm used to solve the bandit problem. The branching heuristic, we call CHB, l...

We have previously shown that targeting human CD34(+) hematopoietic stem cells (HSC) with a bispecific antibody (BiAb) directed against myosin light chain (MLC) increases delivery of cells to the injured hearts and improves cardiac performance in the nude rat. In this study, we have sought to validate our previous observations and to perform more detailed determination of ventricular function i...

The epidermal growth factor receptor (EGFR) is an attractive target for the immunotherapy of EGFR+ tumors. Adjuvant immunotherapy with cytokine-induced killer (CIK) cells may improve progression-free survival rates in patients suffering from cancer. In the present study, we examined the bispecific antibody anti-CD3 x anti-EGFR (EGFRBi-Ab) for its ability to redirect CIK cells to target EGFR-pos...