نتایج جستجو برای: atypical epec

تعداد نتایج: 47438  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2000
B A Vallance B B Finlay

Microbial pathogens have evolved many ingenious ways to infect their hosts and cause disease, including the subversion and exploitation of target host cells. One such subversive microbe is enteropathogenic Escherichia coli (EPEC). A major cause of infantile diarrhea in developing countries, EPEC poses a significant health threat to children worldwide. Central to EPEC-mediated disease is its col...

2018
Yu Zhou Xuhui Zhu Hongyan Hou Yanfang Lu Jing Yu Lie Mao Liyan Mao Ziyong Sun

BACKGROUND Diarrhea is the leading infectious cause of childhood morbidity and mortality. Among bacterial agents, diarrheagenic Escherichia coli (DEC) is the major causal agent of childhood diarrhea in developing countries, particularly in children under the age of 5 years. Here, we performed a hospital-based prospective study to explore the pathotype distribution, epidemiological characteristi...

Journal: :Infection and immunity 1998
C Malstrom S James

Previously we showed that lysates of enteropathogenic Escherichia coli (EPEC) inhibit lymphokine production by mitogen-activated human peripheral blood and lamina propria mononuclear cells. The aims of the present study were to determine whether EPEC-inhibitory factors have similar effects on murine lymphoid populations in order to further delineate the mechanisms of alteration of cytokine prod...

Journal: :Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2011
Francesca Barletta Theresa J Ochoa Erik Mercado Joaquim Ruiz Lucie Ecker Giovanni Lopez Monica Mispireta Ana I Gil Claudio F Lanata Thomas G Cleary

BACKGROUND Enteropathogenic Escherichia coli (EPEC) strains are pediatric pathogens commonly isolated from both healthy and sick children with diarrhea in areas of endemicity. The aim of this study was to compare the bacterial load of EPEC isolated from stool samples from children with and without diarrhea to determine whether bacterial load might be a useful tool for further study of this phen...

Journal: :Infection and immunity 2002
Simon J Elliott Colin B O'Connell Athanasia Koutsouris Carl Brinkley Michael S Donnenberg Gail Hecht James B Kaper

Disruption of the barrier properties of the enterocyte tight junction is believed to be important in the pathogenesis of diarrhea caused by enteropathogenic Escherichia coli (EPEC). This phenotype can be measured in vitro as the ability of EPEC to reduce transepithelial resistance (TER) across enterocyte monolayers and requires the products of the locus of enterocyte effacement (LEE) and, in pa...

2014
Uta Praekelt Rolf Reissbrodt Andreas Kresse Asalapuram Pavankumar Krishnan Sankaran Roger James Mary Jesudason Shalini Anandan Agila Prakasam Veeraraghavan Balaji Shanta Dutta Sanjucta Dutta Thandavarayan Ramamurthy Renate Fischer Peter Sander Reiner Schaumann Armando Navarro Peter Williams

Enteropathogenic Escherichia coli (EPEC) are a major cause of infant diarrhoea in developing countries and a significant public health issue in industrialized countries. Currently there are no simple tests available for the diagnosis of EPEC. Serology of O-antigens is widely used routinely in many laboratories throughout the world, even though it has been known for many years to be an unreliabl...

Journal: :FEMS microbiology letters 2006
Kevin J Spears Andrew J Roe David L Gally

This review covers enteropathogenic Escherichia coli (EPEC) and enterohaemorrhagic E. coli (EHEC) infections, focusing on differences in their virulence factors and regulation. While Shiga-toxin expression from integrated bacteriophages sets EHEC apart from EPEC, EHEC infections often originate from asymptomatic carriage in ruminants whereas human EPEC are considered to be overt pathogens and m...

رامین ابری، ودود رضویلر، افشین جوادی، محمد آهنگرزاده‌رضایی، تقی زهرایی‌صالحی .

سویه­های اشریشیا­کلی انتروتوکسیژنیک معمولاً در کشورهای در­حال­توسعه شایع می‌باشند و علت اصلی اسهال در افرادی هستند که به کشورهای در­حال­توسعه مسافرت می­کنند. تیپ­های بیماریزای انتروپاتوژنیک (EPEC) به­عنوان سویه­هایی تعریف شده­اند که دارای ژن eae هستند ولی ژن­های 1stx  و2stx  را ندارند و می­توانند علت اسهال در انسان و حیوانات باشند. هدف از این مطالعه شناسایی و بررسی میزان اشریشیا کلی جدا شده از ن...

2016
Nobuhito Hayashimoto Takashi Inoue Hanako Morita Masahiko Yasuda Masami Ueno Kenji Kawai Toshio Itoh

Common marmosets (Callithrix jacchus) are frequently used for biomedical research but can be afflicted with diarrhea-a serious and potentially lethal health problem. Enteropathogenic Escherichia coli (EPEC) is thought to be the causative pathogen of hemorrhagic typhlocolitis in common marmosets, but the actual incidence of the disease and the relationship between EPEC and hematochezia are unkno...

Journal: :Allergologia et immunopathologia 2001
P Palmeira S B Carbonare M L Silva L R Trabulsi M M Carneiro-Sampaio

BACKGROUND enteropathogenic Escherichia coli (EPEC) is the main etiological agent of infantile diarrhea in Brazil and other developing countries. Human milk IgA protects newborn intestinal mucosa by inhibiting bacterial adhesion to epithelial cells and this effect is shown by in vitro assays of EPEC adhesion to HEp-2 cultured cells. Bovine milk, if effective in promoting this protection, could ...

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