Background and Objective: Alzheimer’s disease (AD) is one of the most common neurodegenerative diseases and results from the extracellular accumulation of b-amyloid peptides and the resulting neuronal dysfunction. In this study, the role of nicotinic acetylcholine receptors, protein kinase B (PKB) and protein kinase M (PKM) were evaluated in order to examine the mechanism of the protective effe...

Background and purpose: Preeclampsia as the most common complication of pregnancies has unknown physiopathology. Because the role of serum Beta-human Chorionic Gonadotropin (B-hCG) in pathophysiology of preeclampsia is not well known, we decided to determine the correlation between serum concentration of B-HCG and preeclampsia . Materials and Methods: This case-control study performed on t...

The radioactive contamination measurement is essential in nuclear facilities. Monitoring of low level alpha and beta contamination is possible using light detectors high efficiency. Due to the fact that many detectors canchr('39')t simultaneously discriminate alpha, beta and gamma rays; among existing methods, phoswich detectors would be appropriate option to measure different radioactive conta...

Background and Aim:  Dysmenorrheaorpainful menstruation of the most common complaints of the women's. Considering the effect of β-endorphin on reducing the pain of menstruation, the purpose of this study was to investigate changes in β-endorphin and severity of primary dysmenorrhea pain following aerobic exercise with and without consumption of cumin in non-athlete girls Materia...

   Background and Aim: About 13 beta-globin mutations encompass 70-90% of the mutation spectrum in Iran. These mutations are called common beta-globin mutations. The rest are rare or unknown mutations. The objective of this study was to identify the rare or unknown beta-globin mutations in Qazvin province.   Materials and Methods: In this descriptive-analytic study, EDTA-containing venous blood...

Background & aims: Some studies have shown that beta-alanine supplementation may delay fatigue during strenuous exercises. The aim of this study was the effect of 10 days β-alanine supplementation with different doses on neuromuscular fatigue and blood lactate levels. Material & methods: 40 active men with a mean age of 21.9±2.6 years and body mass index 24.54±1.8 kg/m2 were ...

Background and Aims: Chondrocytes and their differentiation play a central role in joint diseases. Effect of the transforming growth factor (TGF)-β1 on chondrocyte characteristics and differentiation is not clearly understood. This study was undertaken to investigate the effects of TGF-β1 on tissue characteristics and morphology of chondrocytes against degradation induced by interleuk...