Cocrystals can be used as an alternative approach based on crystal engineering to enhance specific physicochemical and biopharmaceutical properties of active pharmaceutical ingredients (APIs) when the approaches to salt or polymorph formation do not meet the expected targets. In this article, an overview of pharmaceutical cocrystals will be presented, with an emphasis on the intermolecular inte...

Hydrogels are promising biomaterials because of their important qualities such as biocompatibility, biodegradability, hydrophilicity and non-toxicity. These qualities make hydrogels suitable for application in medical and pharmaceutical field. Recently, a tremendous growth of hydrogel application is seen, especially as gel and patch form, in transdermal drug delivery. This review mainly focuses...

Classical multicomponent preparations mostly derived from traditional usages in Western and Eastern phytotherapy have been under-evaluated for a long time as potential new pharmaceutical products. The regulatory scenario, in particular at the European level, has only recently considered these aspects proposing harmonized guidelines for the pharmaceutical registration of traditional herbal produ...

like other sciences, market segmentation, as a science, seeks to realize unique needs of human being. in health market, individual diagnostic and curative methods are practiced more than anytime. however, a foundation of this market, pharmaceutical market, is not as advanced as other products and services markets in terms of segmentation. regarding the complexity of pharmaceutical market, it is...

Drug has a great and crucial role inboth the health systems and the quality of life, and thereforeits shortage can cause death.In order to the important role of drugs,pharmaceutical supply chain(PSC) shouldensure that drugs are delivered to people in the right time with the best quality.On the other hand, thesupply chain (SC) members depend on each other for resources and information, and it ha...

Objective(s):Cefixime (Cfx), is a semi-synthetic third-generation oral cephalosporin antibiotic that is prescribed for the treatment of susceptible infections. There are some procedures for the determination of Cfx in pharmaceutical formulations and biological samples. Herein a spectrofluorimetric method was proposed for Cfx determination based on the fluorescence quenching of terbium-danofloxa...

The pharmaceutical area can present some opportunities for mechanical engineers to develop a vast type of dosage forms particularly novel forms like nanoparticles. The classical education of mechanics needs some alterations to prepare appropriate education courses in this regard. In order to present some views about this issue, we collect some information around the importance of mechanical eng...

Molecular farming technology offers a unique advantage that almost any protein can be produced economically and safely under very controlled conditions. Besides traditional production systems, such as bacteria, yeasts, insects and mammal cell lines, plants can now be used to produce eukaryotic recombinant proteins, especially therapeutic ones. Their advantages as hosts for protein production in...

Objective: Pharmaceutical chemistry plays a key role in pharmaceutical speciality, which is aiming at making students master basic concepts, basic theory and basic skills of pharmaceutical chemistry. The teachers, however, often encounter some challenges in their teaching process, such as insufficient learning motivation for students, lack of effective means to achieve teaching goals, non-unifo...

in this study a sensitive, simple and accurate spectrophotometric method was suggested for determination of tamsulosin in bulk powder and pharmaceutical dosage form based on the formation of an ion-pair complex between the drug and bromocresol green in a buffer solution at ph 3.5. the formed yellow color complex was extracted with chloroform and measured at 415 nm. the optimum reaction conditio...