Introduction Ano-rectal bleeding is a common symptom which may be associated with local conditions such as haemorrhoids and fissures but may also be the presenting symptom with neoplasia, diverticular disease or inflammatory disease of the colon or rectum. Many patients with rectal or colonic disease have associated symptoms such as change of bowel habit or loss of weight, and it is uncertain h...

In a randomised double blind trial, the effect on growth and clinical status of a nutrient enriched 'post-discharge' milk formula versus a standard term formula, was compared in 32 exclusively bottle fed preterm infants. The formulas were used as the sole milk intake up to a postnatal age of 9 months. Significant increases in linear growth and weight gain were observed in the infants who receiv...

country, in which he has been actively employed for about 28 years. Dr. W. H. Harrisin his notes, says :?" On October 15th, at about 1 a m., while attending a lady in her confinement, I received a note from a friend of D. F's informing me that Mr F. was in great pain with what he believed to be constipation, which, after coming on in paroxysms for about a couple of hours seemed to have settled ...

Over a five-and-a-half-year period, there were 298 laboratory requests for urinary 5-hydroxyindoleacetic acid (5-HIAA). The clinical and laboratory associations of the 24 patients in which there were 43 urinary 5-HIAA 24-h collection results greater than the laboratory upper reference limit are detailed. Four were confirmed carcinoid tumours and two were phaeochromocytomas. Flushing was a promi...

, Pr. Harrold: This man was 68 when he died. He was a gentlemen's outfitter. Before illness he had had two hernia repairs, and during the 1914-1918 war he had had afew injuries to the arms and legs. He had also had a brief episode of jaundice. His final illness began in the summer of 1962. He died in the summer of 1963. In J962 he noticed the onset of progressive mild exertional dyspnoea. In No...

Pelvic colonic pressures were recorded before, during, as well as after a meal in patients with non-specific diarrhoea (12) or constipation (14), who were selected according to strict clinical criteria of bowel habit. In the basal state diarrhoeal patients as a group had significantly less colonic activity than constipated patients, but the overlap was considerable. During the meal colonic acti...

The prevalence and significance of colorectal symptoms within a group of 1533 individuals was assessed using a self-completion questionnaire and results compared with faecal occult blood screening. One hundred and twenty eight individuals listed one or more symptoms, while only 12 had a positive blood occult test. Of the subjects studied, 6.6% had noticed bleeding from the rectum in the last si...

The effect of ispaghula husk on colonic motility of the right and left side was examined in 10 patients with left sided diverticular disease using an untethered pressure sensitive radiotelemetry capsule. After treatment, ispaghula husk reduced mouth to rectum transit by a median of 8.8 hours and the time to midtransverse colon by five hours. In the right colon there was an increase in the media...

Ninety nine healthy young volunteers (58 men, 34 women, aged 17-27 years) answered a questionnaire concerning their bowel habit with particular reference to the effects of beverages. Twenty nine per cent (63% women) claimed that coffee induced a desire to defecate. The rectosigmoid motor responses to black, unsweetened coffee were then investigated by multiport manometry in 14 healthy-subjects ...