Endosomal protein sorting controls the localization of many physiologically important proteins and is linked to several neurodegenerative diseases. VPS35 is a component of the retromer complex, which mediates endosome-to-Golgi retrieval of membrane proteins such as the cation-independent mannose 6-phosphate receptor. Furthermore, retromer is also required for the endosomal recruitment of the ac...

C. 2. c. EFFLUENT VERSUS ABSORPTION AREA WATER QUALITY DURING THE RESEARCH STUDY Hydrogen ion concentrations (pH), EC values, and chloride ion concentrations remained consistent between effluent and subsystems samples each year. Effluent nitrate-N concentrations were lower and ammonium-N concentrations higher than those concentrations found within either subsystem in the absorption area. This w...

Worldwide, wild fish living in rivers receiving municipal and industrial discharges may experience endocrine disruption as a result of exposure to anthropogenic pollutants. The purpose of this study was to evaluate the hormonal status of wild fish in a U.S. river receiving unbleached kraft and recycled pulp mill effluent (Pearl River at Bogalusa, LA). We evaluated two alternative hypotheses: th...

Commercial nuclear power plants release gaseous and liquid radiological effluents into the environment as a byproduct of electrical generation. These releases are monitored by federal agencies to ensure compliance of regulatory limits. The U.S. Nuclear Regulatory Commission (NRC) and U.S. Environmental Protection Agency (EPA) offer guidance and make recommendations for domestic power plants eff...

The use of effluent bioassays in various international jurisdictions is reviewed, resulting in an analysis of themes and trends in: regulatory use, different uses of bioassays in meeting protection goals, different types of bioassays, bioassay test variability, statistical design, use of effluent bioassays to predict receiving environment effects, and uptake of effluent bioassay testing by deve...

The effect of indigo dye effluent on the freshwater microalga Scenedesmus quadricauda ABU12 was investigated under controlled laboratory conditions. The microalga was exposed to different concentrations of the effluent obtained by diluting the dye effluent from 100 to 175 times in bold basal medium (BBM). The growth rate of the microalga decreased as indigo dye effluent concentration increased ...

The present investigation was carried out during 2009-2010 to characterize and assess the treated paper mill effluent from The Tamilnadu Newsprint and Papers Limited (TNPL) for physico-chemical and biological properties. Treated paper mill effluent samples were collected from TNPL, Kagithapuram, Karur District of Tamil Nadu and were analyzed in the Department of Environmental Sciences, Tamil Na...

Drosophila immune cells, the hemocytes, undergo four stereotypical developmental migrations to populate the embryo, where they provide immune reconnoitering, as well as a number of non-immune-related functions necessary for proper embryogenesis. Here, we describe a role for Rho1 in one of these developmental migrations in which posteriorly located hemocytes migrate toward the head. This migrati...

The authors conducted a set of survey on wash load transportation at the two sites in the Hinuma River, during a fl ood on June 19th ,1997, and found out a decrease in wash load concentration between the upper site(46.0km) and the lower site(28.1km). A numerical simulation was carried out to investigate causes of the decrease. CIP scheme was introduced to solve the unsteady advection-diffusion ...