نتایج جستجو برای: chromosomal damage

تعداد نتایج: 270697  

Journal: :International Journal of Occupational Medicine and Environmental Health 2012

Journal: :Nature communications 2015
Petros Marangos Michelle Stevense Konstantina Niaka Michaela Lagoudaki Ibtissem Nabti Rolf Jessberger John Carroll

In mammalian oocytes DNA damage can cause chromosomal abnormalities that potentially lead to infertility and developmental disorders. However, there is little known about the response of oocytes to DNA damage. Here we find that oocytes with DNA damage arrest at metaphase of the first meiosis (MI). The MI arrest is induced by the spindle assembly checkpoint (SAC) because inhibiting the SAC overr...

Bisphenol-A (BPA) is an industrial xenoestrogen used widely in our living environment. Recently, several studies suggested that BPA has destructive effects on DNA and chromosomes in normal body cells via estrogen receptors (ER). Therefore, BPA could be considered as an important mediator in many diseases such as cancer. However, there are still many controversial issues which need clarification...

Journal: :مجله دانشکده پزشکی دانشگاه علوم پزشکی تهران 0
پریسا کلانتری kalantari p حوری سپهری sepehri h محمدتقی اکبری akbari mt زهرا اوسطی آشتیانی osati ashtiani z فرخنده بهجتی behjati f

in this study, chromosome analyses were performed on 70 infertile azoospermic and oligospermic (<20 million/ml) men, and also cultures of peripheral blood lymphocytes by high resolution banding method were analysed as well. it is revealed 8 (11.43 percent) men with chromosomal abnormality. there were 31.4 percent patients with azoospermia and 68.6 percent with oligospermia from several thousand...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید