نتایج جستجو برای: chronic inflammatory demyelinating polyradiculoneuropathy
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according to CIDP Disease Activity Status (CDAS) [4, 6] . Twelve healthy volunteers were used as controls (‘Ctrl’ group). Skin punch biopsies were performed 10 cm above the external malleoli and snap frozen in liquid nitrogen. RNA extraction, gene expression profiling, and MetaCore ® data analysis were performed according to the methods described previously [4] with the following filters: fold ...
Matrix metalloproteinases (MMPs) and the cytokine tumour necrosis factor (TNF)-alpha are implicated in the pathology of inflammatory demyelinating diseases of the CNS, and may also be involved in peripheral demyelinating diseases such as acute inflammatory demyelinating polyradiculoneuropathy. We have tested an inhibitor of MMP activity and TNF-alpha processing, BB-1101, in experimental autoimm...
Objective To emphasize recognition of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) due to Immune checkpoint inhibitor (ICI) therapy Atezolizumab and efficacy steroids in treatment. Background is an anti-programmed death-ligand 1 (PD-L1) immune-modulating drug that induces tumor-specific cytotoxic T-cell immunity against the PD-L1 overexpression many aggressive lung cancers. ...
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an autoimmune disease presenting with weakness and numbness in a remitting or chronic progressive course. It is known to have several clinical presentations and several associated diseases. CIDP has been associated with multiple myeloma, monoclonal gammopathy of undetermined significance (MGUS), and other paraproteinemias. We p...
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