Background: Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women of reproductive age. PCOS characterized by hyperandrogenism and oligomenorrhea, .It a cause female subfertility. Anti-mullerianhormone (AMH) 2-4 times higher patients with compared to normal subfertilety patient.
 Objective: To assess impact metformin oral contraceptives (OCs) containing cyproterone ace...

OBJECTIVE To compare the effect of letrozole with combined metformin and clomiphene citrate (CC) for ovulation induction in CC-resistant women with polycystic ovary syndrome (PCOS). DESIGN A randomized controlled trial. SETTING University teaching hospital and a private practice setting. PATIENT(S) Two hundred fifty anovulatory women (582 cycles) with CC-resistant PCOS. INTERVENTION(S) ...

At present, it is unclear what the role is of laparoscopic ovarian diathermy (LOD) and of metformin administration as second-line treatments for ovulation induction in women with polycystic ovary syndrome (PCOS) after failure of clomiphene citrate (CC) treatment. The aim of the present study was to compare in a randomized double-blind placebo-controlled fashion the effectiveness of LOD with met...

We report the case of a 35 year old women who developed a complex paranoid delusion during the course of clomiphene treatment für ovulation. The psychopathology was remarkable, because after a short hypomanic period the patient was without severe cognitive disturbance but struggled with a complex monothematic delusion. The delusion vanished in the course of a combination treatment with olanzapi...

background: although heterotopic gestation is common in assisted reproductive techniques, it is very rare in natural conception and clomiphene induced pregnancy. diagnosis and appropriate intervention of heterotopic pregnancy requires a high index of suspicious. case: in this paper a case of heterotopic pregnancy in a 30-year old woman with hemoperitoneum from ruptured tubal pregnancy with live...

Background: It is assumed in polycystic ovary syndrome (PCOS) that follicular development, maturation, ovulation and implantation are impaired due to hormonal imbalance and vascular impairment of the ovarian and uterine vasculatures. The mechanism of action of laparoscopic ovarian drilling (LOD) is largely unexplained. To date, only limited studies have been conducted utilizing 3D ultrasonograp...

This paper presented a 28-year-old female with systemic sclerosis who developed scleroderma renal crisis and ovarian hyperstimulation syndrome following clomiphene administration. Urgent therapy including angiotensin-converting enzyme (ACE) inhibitors and supportive care resulted in regression and eventually resolution of all the clinical and laboratory symptoms. Although scleroderma renal cris...

■ EVIDENCE-BASED ANSWER Short-term use of metformin (Glucophage) improves ovulation rates for women with polycystic ovary syndrome (PCOS) (strength of recommendation [SOR]: A, based on systematic reviews of randomized controlled trials [RCT]). Metformin also decreases menstrual irregularities (SOR: B, extrapolated from a systematic review). When added to clomiphene, metformin increases ovulatio...