background: infertility affects about 10-15% of reproductive-age couples. about half the causes of infertility are female related and approximately 40% of the cases are caused by anovulation, mostly in pco women. objective: this study was conducted to determine and compare the effects of two drug treatment regimens: higher dose of clomiphene and a combination of lower dose of clomiphene and tam...

Background To evaluate the effect of metformin on ovulation and pregnancy rate in clomiphene citrate resistant women with polycystic ovary syndrome (PCOS). MaterialsAndMethods In this clinical trial each patient, regarding her previous resistance to Clomiphene, served as her own control. A total of 35 clomiphene citrate resistant PCOS patients, referring to Royan institute were studied. Clomiph...

objective: to determine the efficacy of ovarian drilling in pco patients who failed to achieve pregnancy with medical treatment. methods and main results: 75 patients with a diagnosis of pco of whom 48(64%) were primary infertile and 27(36%) were secondary infertile were clomiphene resistant. the other methods like bromocriptin, gonadotropins, gnrh -a and metformin had been given to these patie...

Background: To evaluate the effect of metformin on ovulation and pregnancy rate in clomiphene citrate resistant women with polycystic ovary syndrome (PCOS). Material & Methods: In this clinical trial each patient, regarding her previous resistance to Clomiphene, served as her own control. A total of 35 clomiphene citrate resistant PCOS patients, referring to Royan institute were studied. Clomip...

BACKGROUND Polycystic ovary syndrome (PCOS) is associated with approximately 75% of women who suffer from infertility due to anovulation. Additionally, around 20- 25% of anovulatory women with PCOS do not respond at all to clomiphene citrate and are considered to be "clomiphene- resistant". Aromatase inhibitors have been suggested as an alternative treatment to clomiphene as the discrepancy bet...

INTRODUCTION Polycystic ovary syndrome is the most common endocrinopathy in women of reproductive-age. Therapy for those who want to get pregnant involves ovulation induction using clomiphene citrate, metformin, letrozole and gonadotropins. OBJECTIVE The aim of the study was to compare the efficacy of combinations of clomiphene citrate-metformin and letrozole-metformin in obese patients who a...

clomiphene critrate is an effective and safe treatment for anovulation, but in some cases resistance occurs. to evaluate the efficacy of dexamethasone in resistant anovulatory normal dehydroepiandrosterone patients, we prospectively studied 57 infertile resistant anovulatory women. each woman received 100 mg daily clomiphene critrate from cycle days 3-7 and 0.5 mg dexamethasone from cycle days ...

Aim Polycystic ovary syndrome (PCOS) is an ovulatory disorder and insulin resistance and diabetes are involved in its pathophysiology. Metformin, an anti-diabetic agent, has been reported to be useful to induce ovulation. Methods Metformin treatment was classified into four types: (1) clomiphene-metformin combination treatment for clomiphene-resistant patients; (2) clomiphene-metformin combin...