Ectopic thyroid tissue refers to presence of thyroid tissue at locations away from the normal site in the pretracheal region in the lower neck. Few of such cases are associated with a functioning thyroid gland in its normal anatomical location. However in many cases, the ectopic thyroid gland is the only functioning thyroid. Radionuclide scan is mandatory when dealing with an ectopic thyroid le...

Introduction/Objective. Alcohol abuse influence on developing thyroid cancer is controversial. While some studies consider it a protective factor, others deny any impact cancer. The objective of the paper was to establish possible link between alcohol and certain types cancers. Methods. retrospective study included 502 patients with control group 600 benign forms diseases (e.g. nodular, multino...

Nodular lesions can be difficult to diagnose under dermoscopy alone, since they often lack specific diagnostic features. Confocal microscopy can be used as an aid to dermoscopy, to increase the diagnostic accuracy on equivocal skin lesions. We report three cases of bluish nodular lesions, difficult to diagnose under dermoscopy alone. Confocal features were very useful in these cases to lead us ...

Surgical Treatment. -By Israel Bram, m.d. C. V. Mosby Company, St. Louis, 1920. Thk author should entertain no fear that his book may not be tolerated: it rather requires a welcome. The whole subject of Graves' disease is carefully reviewed: no new theories of its pathogenesis are advanced, but the author inclines to the view that the hyperthyroidism of the disease is itself an incidental produ...

We evaluated the ability of new thyrotropin (TSH) assays to separate hyperthyroid (n = 50) patients from clinically euthyroid subjects with low TSH values (nodular goiter, n = 20, and nonthyroidal illness, n = 22). Only patients whose serum TSH was < 0.1 mIU/L by immunoradiometric assay were included. We used a new immunofluorometric method based on time-resolved fluorescence (TR-IFMA) and a ne...

OBJECTIVE To evaluate the significance of BRAF (V600E) and Ras mutations, and RET rearrangements in papillary thyroid cancer (PTC) in the South central region of China. METHODS We included patients from Union hospital's pathology archive diagnosed with PTC and meeting the criteria for BRAF mutation, RAS mutation, and RET rearrangement testing. Medical records were analyzed for BRAF and RAS mu...

Early continuous hormonal treatment, inhibiting TSH secretion, reduces the volume of recent homogeneous goiters. This treatment is usually well tolerated, but can induce thyrotoxicosis in subjects with blunted response of TSH to TRH stimulation before treatment. Surgery is used for large goiters, compressive goiters or suspicion of cancer and after failure of the hormonal treatment. In all case...

Intrathoracic goiters generally occupy anterior mediastinum, rarely involving the posterior mediastinal space. Reported herein is a 54-year-old female with a giant posterior mediastinal mass that was successfully resected via right posterolateral thoracotomy. The final pathologic diagnosis was giant posterior mediastinal goiter. This patient has done well postoperatively, with no evidence of lo...

Sporadic nontoxic goiter (SNG) is defined as a benign enlargement of the thyroid gland in a euthyroid subject living in an iodine-sufficient area. Such goiters can be diffuse, uninodular, or multinodular and can vary greatly in size at presentation, growth rate, and symptomatology. The causes of SNG are incompletely understood, but include autoimmune, genetic, and extrinsic factors. SNG is a co...

Although iodine prevents goiter, enlarged thyroid glands continue to be detected in subjects, especially children, in spite of adequate iodine ingestion. Iodine may cause goiter in susceptible individuals by inhibiting the organic binding of iodine as is seen in adult asthmatics, neonates born of iodine ingesting mothers and in subjects residing along the littoral of Japan. Myxedema, especially...