Background. Desnutrin is an enzyme that catalyzes the first step of cytoplasmic triacylglycerol lipolysis from white adipose tissue and several other tissues, which are disrupted by the obesity and metabolic syndrome. Objectives. The aim of this study was to compare the effect of high-intensity interval training and continuous training on the desnutrin gene expression in the subcutaneous adipo...

In this paper we study the pricing problem of multiple exercise options in continuous time on a finite time horizon. For the corresponding multiple stopping problem, we prove, under quite general assumptions, the existence of the Snell envelope, a reduction principle as nested single stopping problems, and a Doob-Meyer type decomposition for the Snell envelope. The main technical difficulty ari...

Following peripheral nerve injury, synapses are withdrawn from axotomized motoneurons. Moderate daily treadmill exercise, which promotes axon regeneration of cut peripheral nerves, also influences this synaptic stripping. Different exercise protocols are required to promote axon regeneration in male and female animals, but the sex requirements for an effect of exercise on synaptic stripping are...

Methods The data was collected in a cross-sectional study with 103 T2D adults during the year 2009 (April to November). The Program had provided two weekly sessions of multidisciplinary health educational interventions with several modalities of supervised physical exercise (60min each one) and register of post-prandial (i.e. pre-exercise) and post-exercise BG. HbA1c between the stage of the st...

Estimation of exercise tolerance in patients with heart disease and significant symptoms can usually not be expressed in terms of maximal oxygen uptake or power at a fixed heart rate calculated from a 'steady state' exercise test. The exercise tolerance can be expressed only by the maximal power developed, when limited by symptoms. For this purpose the level of tolerance is better assessed by a...

Aerobic exercise positively impacts cardiometabolic risk factors and diseases; however, the most effective exercise training strategies have yet to be identified. To determine the effect of high intensity (interval) training (HI(I)T) versus moderate intensity continuous exercise (MICE) training on cardiometabolic risk factors and cardiorespiratory fitness we conducted a 16-week crossover RCT wi...

A controlled double-blind clinical evaluation of oxprenolol, a new beta-adrenergic blocking drug, has been carried out in I3 patients with angina pectoris. Objective assessment was based on exercise on a treadmill with continuous radiocardiographic monitoring. The dose of oxprenolol was 8o mg three times a day. There was a significant reduction of the degree of ischaemic ST depression during ex...

We examined vascular function in an inactive muscle bed, the forearm, during lower limb exercise and determined the contribution of endothelium-derived nitric oxide (NO) to the hyperemic response. Eight young males were randomized to participate in two studies, each consisting of two bouts of lower limb exercise, separated by a 30-min recovery. Peak forearm blood flow (PFBF) and mean blood flow...