The trigeminal nerve gives rise to the corneal subbasal system, which plays a crucial role in sensations of touch, pain, and temperature ocular healing processes. Technological advancements instruments, particular vivo confocal microscopy aethesiometry, have allowed for structural functional evaluation nerves health disease. Through application these technologies humans animal models, abnormali...

Treating various ailments of eye utilizes mostly two strategies i.e. delivery of the therapeutic agent by development of a novel delivery system or by enhancing the permeation of therapeutically active agent by the use of penetration enhancers or by the alteration of its physicochemical properties. Conventional ophthalmic drugs delivery system including eye drops, ointments and gels, are no lon...

PURPOSE To evaluate the long-term outcome of HLA-matched lr-CLAL for bilateral ocular surface disorders. METHODS A retrospective, non-comparative interventional case series study of 39 eyes of 32 patients with bilateral surface disorders and clinical diagnosis of limbal stem cell deficiency who underwent HLA-matched lr-CLAL. Visual acuity (VA), ambulatory vision (> or = 20/200) and ocular sur...

Objective- To compare the effects of topical eye-drop and subconjunctival administration of diclofenac on improvement of experimental corneal alkali wound in rabbits eyes. Design- Experimental study. Animal- fifteen rabbits. Procedures- Alkali wounds were inflicted on the central corneas of 15 rabbits which we...

Background: To evaluate the agreement in intraocular pressure (IOP) measurements by Ocular Response Analyzer (ORA) and Tono-Pen XL (TXL) with the Goldmann Applanation Tonometer (GAT) and to examine corneal biomechanical properties in aphakic glaucoma patients with a central corneal thickness (CCT) >600 µ. Methods: Thirty-six eyes of aphakic glaucoma patients (group 1) and 40 eyes of normal chil...

Chloroquine is frequently used to treat systemic autoimmune diseases, such as systemic lupus erythematosus (SLE). With long term treatment, associated toxicity is well known, with retinopathy been the most common complication. Other chronic complications include skin disorders (hyperpigmentation), blood dyscrasias, corneal deposits, encephalopathy, neuropathy, myopathy, and impairment of audito...

Keratoconus has been associated with various ocular and systemic disorders. It has been linked, in a few cases, with floppy eyelid syndrome (a disorder characterized by a soft rubbery upper tarsus, papillary conjunctivitis and obesity). A 40-year-old male presented with a complaint of gradually decreasing vision in the right eye. An intermittent right exotropia had become constant and he was un...

Objectives: Owing to the increasing number of patients suffering from posterior eye disorders, efficient medicine delivery segment is now in great demand clinical services. With unmet medical requirements, an important therapeutic target. So, physicians should be informed new indications and current strategies drug when technologies enter market.
 Summary: The most common causes vision imp...