stem cell therapy has been applied for the treatment of degenerative diseases encompassing corneal disorders.this consideration is regarding the unique characteristics of stem cells including self-renewal and pluripotency. some corneal diseases result from deficiencies in the limbal region. in these conditions, limbal stem cell therapy is considered in which limbal stem cells are cultured in vi...

PURPOSE Amniotic membrane transplantation is currently being used as an alternative approach to treat severe corneal surface disorders refractory to medical therapy. The authors report complications of corneal surface disorders after successful amniotic membrane transplantation. METHODS Case series. RESULTS Twenty-eight patients with corneal surface disorders due to severe chemical burns, c...

The condition of the corneal epithelium is a critical determinant of corneal transparency and clear vision. The corneal epithelium serves as a barrier to protect the eye from external insults, with its smooth surface being essential for its optical properties. Disorders of the corneal epithelium include superficial punctate keratopathy, corneal erosion, and persistent epithelial defects (PEDs)....

PURPOSE To report a case of corneal perforation associated with oral administration of erlotinib and its spontaneous healing after temporary discontinuation of drug treatment. CASE REPORT A 65-year-old man with metastatic lung cancer was treated with erlotinib (150 mg/day), a specific tyrosine kinase inhibitor of the epidermal growth factor receptor. He was referred to our corneal service for...

One among the corneal diseases causing significant visual impairment and blindness is corneal dystrophies, which is a heterogeneous subset of hereditary corneal disorders that are generally bilateral, non-inflammatory and often result in corneal opacities, requiring corneal transplantation [1]. To add to this group and also which is closely related to dystrophy are the degenerative conditions o...