Crystallization is a widely used technology for solid-liquid separation in the process industry. It is extensively used in the production of pharmaceuticals to separate the drug from the solvent mixture as well as to ensure that the drug crystal product conforms to size and morphology specifications. The crystal size in crystallization processes is one of the most important variables since it i...

A morphological population balance model is applied to crystallisation of hen-egg white lysozyme (HEWL) for investigating the effects of seed loading and cooling rate on supersaturation, crystal size and shape distribution. Growth rates of individual faces and final crystal size and shape distribution were examined under varied seeding and cooling conditions. It was found that for growth only c...

Martensitic transformation usually creates hierarchical internal structures beyond mere change of the atomic crystal structure. Multi-stage nucleation is thus required, where nucleation (level-1) of the underlying atomic crystal lattice does not have to be immediately followed by the nucleation of higher-order superstructures (level-2 and above), such as polysynthetic laths. Using in situ trans...

Statistical models were developed to reveal which structural elements of ice cream affect melting rate and hardness. Ice creams were frozen in a batch freezer with three types of sweetener, three levels of the emulsifier polysorbate 80, and two different draw temperatures to produce ice creams with a range of microstructures. Ice cream mixes were analyzed for viscosity, and finished ice creams ...

With the rapid increase in crystal structures of protein-protein complexes deposited in the Protein Data Bank (PDB), more and more crystal contacts have been shown to have similar or even larger interface areas than biological interfaces. However, little attention has been paid to these large crystal packing contacts and their structural principles remain unknown. To address this issue, we used...

Crystallization of metformin hydrochloride by solvent evaporation method was carried out in the presence of hydrophilic and hydrophobic polymers to investigate the influence of polymer in the agglomeration of the crystallites in–vitro. Transparent, prismatic shaped crystals (of size: 7 × 2 × 1.5 mm3) were crystallized in hydrophilic polymer hydroxypropyl methylcellulose (HPMC) and long rod shap...

We developed a simple method to fabricate colloidal crystal heterostructures (CCHs) with two or three stacked poly(methyl methacrylate) (PMMA) particle two-dimensional (2D) colloidal monolayer arrays of different particle spacings that independently diffract light. The 2D colloidal monolayer arrays of PMMA were prepared by using the air/water interface self-assembly method we recently developed...

A new polymorph crystalline silica composition having uniform pore dimensions were synthesized by calcining a crystalline hydrated alkyl-ammonium silicate. The pore dimensions approximately were 6 angstrom for silicalite-1 and 11 angstrom for silicalite-2 units. The silicalite-1 was prepared hydrothermally at a pH of about 10 from a reaction mixture consist of water, amorphous silica and a ...