OBJECTIVE To compare the diagnostic performance of digital breast tomosynthesis (DBT) and conventional breast ultrasound (US) to characterize breast lesions as benign or malignant. MATERIALS AND METHODS A total of 332 women, presenting for screening examinations or for breast biopsy between March and June 2012 were recruited to undergo digital mammography (DM), DBT, and breast US examination....

Digital breast tomosynthesis (DBT) is an emerging modality for breast imaging. A typical tomosynthesis image is reconstructed from projection data acquired at a limited number of views over a limited angular range. In general, the quantitative accuracy of the image can be significantly compromised by severe artifacts and non-isotropic resolution resulting from the incomplete data. Nevertheless,...

DNA-binding proteins play crucial roles in various biological processes, such as DNA replication and repair, transcriptional regulation and many other biological activities associated with DNA. Experimental recognition techniques for DNA-binding proteins identification are both time consuming and expensive. Effective methods for identifying these proteins only based on protein sequences are hig...

Digital breast tomosynthesis (DBT) was developed to alleviate the problem of overlapping tissue in 2-D mammography. To improve DBT image quality, we are developing model-based iterative reconstruction method based on models of the imaging system physics. Our preliminary implementation (SQS-DBCN) incorporated detector blur into the system model and correlation into the noise model under some sim...

In this research, zeolite Na-Y was synthesized from Kaolin without an organic template under the non-hydrothermal condition to adsorb sulfur compound. Model fuel desulfurization was optimized by employing the Box-Behnken experimental design with 2 center points, the three parameters, and one response value. The objective was to find how sorption capacity is related to alkali fusion temperat...

The design and synthesis is reported for a fluorescent conjugated polymer (CP), poly{[4,4,9,9-tetrakis(4-(octyloxy)phenyl-4,9-dihydro-s-indaceno[1,2-b:5,6-b']dithiophene)]-alt-co-[4,7-di(thiophen-2-yl)-2,1,3-benzothiadiazole]} (PIDT-DBT), with absorption and emission profiles fallen within far-red/near infrared (FR/NIR) region and further demonstrate its application in long-term in vitro cell t...

The development of effective multi-modality imaging methods typically requires an efficient information fusion model, particularly when combining structural images with a complementary imaging modality that provides functional information. We propose a composition-based image segmentation method for X-ray digital breast tomosynthesis (DBT) and a structural-prior-guided image reconstruction for ...

The first circadian-relevant kinase to be identified was DOUBLE-TIME (DBT) in Drosophila, a homolog of vertebrate CKIepsilon, which regulates the progressive phosphorylation and stability of PERIOD (PER) proteins in animals. A negative feedback loop wherein PER directly inhibits the transcriptional activity of the CLOCK-CYCLE (CLK-CYC) heterodimer is central to the generation of molecular rhyth...

LINDA A. DIMEFF, PH.D., is a chief sci­ entific officer at Behavioral Tech Research, Inc., a research organization dedicated to the dissemination of evidence-based prac­ tices (EBPs). She is also a clinical instructor in the Department of Psychology at the Uni­ versity of Washington. Her research inter­ ests include EBPs, addictive behaviors, dialec­ tical behavior therapy (DBT), and the adapta...