High atomic number nanoparticles are of increasing interest in radiotherapy due to their significant positive impact on the local dose applied treatment site. In this work, three types metal were utilized investigate enhancement based GATE Monte Carlo simulation tool. Gold, gadolinium, and silver implanted at different concentrations a 1 cm radius sphere mimic cancerous tumor inside 10 × 30 cm3...

The radiosensitizing potential of gemcitabine (2',2'-difluoro-2'-deoxycytidine) was studied in combination with pulsed low dose-rate irradiation. The experiments were carried out with a human lung carcinoma cell line SW1573. These were irradiated at pulsed low dose rate (p-LDR); the average dose rate was 1 Gy/h. In the experiments with gemcitabine, this drug was applied for 24 h at a concentrat...

BACKGROUND AND PURPOSE Conventional CT angiography (CTA) is acquired during only a short interval in the arterial phase, which limits its ability to evaluate the cerebral circulation. Our aim was to compare the image quality and radiation dose of conventional single-phase CTA (SP-CTA) with a multiphase CTA (MP-CTA) algorithm reconstructed from a perfusion CT (PCT) dataset. MATERIALS AND METHO...