BACKGROUND Although the current standard of care for controlling anaemia and neutropenia during anti-viral therapy for hepatitis C is to use dose reduction of ribavirin and pegylated interferon, respectively, erythropoietin and granulocyte colony-stimulating factor are now being advocated as alternatives to dose reduction. AIM To determine the cost-effectiveness of erythropoietin and granuloc...

This chapter gives an overview of benefit-cost analysis (BCA) and similar evaluation tools, such as cost-effectiveness analysis and technology-based standards, in the context of public health. We describe these evaluation tools, how they are used, their shortcomings, and how they should be interpreted. As with other powerful tools, they are subject to misuse and misinterpretation, even by profe...

OBJECTIVE To evaluate the cost effectiveness of a 4.5 year education campaign that promoted farmers' adoption of rollover protective structures (ROPS) to prevent tractor overturn injuries. DESIGN Randomized controlled trial, decision analysis, and cost effectiveness analysis. SETTING One treatment county and one control county in the State of Kentucky. INTERVENTION A campaign by a local t...

2. Ionizing radiation Individual types of IR possess different biological effectiveness. In order to it unit of equivalent dose was defined – 1 Sievert (Sv). Equivalent dose represents absorbed dose multiplied with factor connected with biological effectiveness of IR. More precisely, this factor expresses how many times is precise IR effective than photons of X or gamma radiation (röentgen radi...

become one of the core components in survival and success of any organization. unfortunately, despite the importance of training evaluation, a small portion of resources are allocated to this matter. among many evaluation models, the cipp model or context, input, process, product model is a very useful approach to educational evaluation. so far, the evaluation of the training courses mostly pro...

With the aim to increase anti-tumor effectiveness of electrochemotherapy, adjuvant immunotherapy with tumor necrosis factor-alpha (TNF-alpha) was tested on tumors in mice. Increased anti-tumor effectiveness on SA-1 tumors was observed after combining TNF-alpha, injected either intratumorally or peritumorally, with electrochemotherapy using suboptimal dose of bleomycin (BLM). The increased anti-...