Purpose. Manuka honey (MH) is an antibacterial agent specific to the islands of New Zealand containing both hydrogen peroxide and a Unique Manuka Factor (UMF). Although the antibacterial properties of MH have been studied, the effect of varying UMF of MH incorporated into tissue engineered scaffolds have not. Therefore, this study was designed to compare silk fibroin cryogels and electrospun sc...

Electrospinning is a versatile technique to prepare polymer fibers in nano to micrometer size ranges using very high electrostatic fields. Electrospun nanofibers with tunable porosity and high specific surface area have various applications, including chromatographic supports for protein separation, biomedical devices, tissue engineering and drug delivery matrices, and as key components in sola...

In this work, electrospinnable and water stable soyprotein was extracted by using a reducing agent in mild alkaline condition, and novel 3D zein and 3D pure soyprotein electrospun scaffolds with three-dimensionally and randomly oriented fibers and large interconnected pores were successfully fabricated by reducing surface resistivity of materials. This unique structure is different from most el...

Doping of titanium dioxide nanofibers by silver nanoparticles revealed distinct improvement in the photocatalytic activity; however other influences have not been investigated. In this work, effect of sliver-doping on the crystal structure, the nanofibrous morphology as well as the photocatalytic activity of titanium oxide nanofibers has been studied. Silver-doped TiO2 nanofibers having differe...

Diseases and disorders associated with nervous system such as injuries by trauma and neurodegeneration are shown to be one of the most serious problems in medicine, requiring innovative strategies to trigger and enhance the nerve regeneration. Tissue engineering aims to provide a highly biomimetic environment by using a combination of cells, materials and suitable biological cues, by which the ...

Electrospinning of collagen and chitosan blend solutions in a 1,1,1,3,3,3-hexafluoroisopropanol/trifluoroacetic acid (v/v, 90/10) mixture was investigated for the fabrication of a biocompatible and biomimetic nanostructure scaffold in tissue engineering. The morphology of the electrospun collagen-chitosan nanofibers was observed by scanning electron microscopy (SEM) and stabilized by glutaralde...

in this work, cofe2o4 nanoparticles have been prepared by co-precipitation technique. the synthesized cofe2o4 nanoparticles were applied in the preparation of cofe2o4/polyacrylonitrile fiber nanocomposites by the electrospinning process. the prepared nanoparticles and nanofibers were characterized using the scanning electron microscopy (sem) and x-ray diffraction methods. the results manifested...

Flexible, magnetic, and hierarchical porous NiFe2O4@SiO2 nanofibrous membranes were prepared by combining the gelatin method with electrospun nanofibers. The membranes exhibited prominent mechanical strength and mesoporosity, as well as multifunctionality of magnetic responsiveness, dye adsorption, and emulsion separation.

Conventional transdermal drug delivery systems (TDDS) have been designed for drug delivery through the skin. These systems use the permeability property of stratum corneum, the outermost surface layer of the skin. Applying polymeric micro and nanofibers in drug delivery has recently attracted great attention and the electrospinning technique is the preferred method for polymeric micro-nanofiber...

Objective(s):The aim of this study was to prepare electrospun nanofibers of celecoxib using combination of time-dependent polymers with pectin to achieve a colon-specific drug delivery system for celecoxib. Materials and Methods:Formulations were produced based on two multilevel 22 full factorial designs. The independent variables were the ratio of drug:time-dependent polymer (X1) and the amoun...