background: jaundice is affecting over 60-80 percent of neonates in the first week of life. glucose-6-phosphate dehydrogenase (g6pd) deficiency, which is an important cause of pathologic hyperbilirubinemia, can lead to hemolytic anemia, jaundice and kernicterus. the present study was performed to determine the prevalence of g6pd deficiency among icteric neonates in shirvan, iran. methods: this ...

G6PD is rate limiting enzyme in pentose phosphate pathway (PPP), have effective physiological role supply of NADPH by converting it into Glucose-6-phosphate to phospogluconate which acts as a major cell reductant and useful survival. Brain highly sophisticated organ our body requires continuous energy form glucose. Daily requirement brain glucose 120gm. plays key it. According WHO 75% world pop...

BACKGROUND Human glucose 6-phosphate dehydrogenase (G6PD), active in both dimer and tetramer forms, is the key entry enzyme in the pentose phosphate pathway (PPP), providing NADPH for biosynthesis and various other purposes, including protection against oxidative stress in erythrocytes. Accordingly haemolytic disease is a major consequence of G6PD deficiency mutations in man, and many severe di...

Background and Aim: Jaundice is a common disorder in neonates and one of the provable causes of glucose-6-phosphate dehydrogenase (G6PD) deficiency, some mutation types of which may be associated with severe neonatal icter. In this line, the present study has been conducted to compare G6PD mutations in incteric and non icteric neonates. Materials and Methods: This case-control study was imple...

The Mediterranean variant of glucose-6-phosphate dehydrogenase (G6PD) is functionally deficient and found in a variety of cell types of affected individuals, including both erythocytes and neutrophils. To determine if the presence of this sex-linked gene is associated to any degree with the occurrence of severe bacterial infection, a study of hospitalized male patients in Iran was undertaken. A...

Objective: To determine the prevalence of Glucose 6 Phosphate Dehydrogenase (G6PD) deficiency in Malak Din Khel subtribe, biggest subtribe Afridi, with expectations newer findings area medicine and research.Study Design: Cross-sectional study.Place Duration Study: This study was conducted District Khyber from March 2018 to August 2018.Materials Methods: The sample size this 177 preschool-going ...

BACKGROUND Riboflavin status is commonly measured by the in vitro stimulation of erythrocyte glutathione reductase with flavin adenine dinucleotide and expressed as an erythrocyte glutathione reductase activation coefficient (EGRAC). However, this assay is insensitive to poor riboflavin status in subjects with glucose-6-phosphate dehydrogenase (G6PD) deficiency. Because G6PD deficiency is commo...

sixty-six children with g6pd deficiency were evaluated retrospectively to ascertain the clinical features, etiology, ultimate outcome and population at risk, the occurrence of jaundice in 18 neonates (group j) was, contrary to other countries, in the form of neonatal jaundice type ii. sepsis, prematurity, hypoxia and acidosis were associating factors. 77.8% of neonates had exchange blood transf...

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BACKGROUND There is a paucity of information regarding glucose-6-phosphate dehydrogenase (G6PD) deficiency in endemic areas for malaria in Latin America. METHODOLOGY/PRINCIPAL FINDINGS This study determined the prevalence of the G6PD deficiency in 200 male non-consanguineous individuals residing in the Ismail Aziz Community, on the outskirts of Manaus (Brazilian Amazon). Six individuals (3%) ...