We have developed a novel diagnostic technology to monitor the human cytomegalovirus (HCMV)-specific CD8+ T-cell responses that is based on the detection of secreted interferon-gamma (IFN-gamma) in the whole blood (referred to as QuantiFERON -CMV). Evaluation of QuantiFERON -CMV in healthy individuals revealed that this technology was at least as sensitive and with some HCMV epitopes more sensi...

Ziff, Schmid, Lewis, and Tanner (1958) first reported that rheumatoid factors reacting with human Cohn fraction II gamma globulins assessed by means of a latex-fixation test (LEI) were aggregated in the families of hospital patients with rheumatoid arthritis. This evidence for familial aggregation was confirmed by Ball and Lawrence (1961) in the urban population sample of Leigh, England, the te...

The marginal proportional hazards frailty model for multivariate failure time data characterizes the intracluster dependency with the frailty model while formulating the marginal distributions with the proportional hazards model. The gamma frailty distribution has been widely used to model intracluster dependency because of its simple interpretation and mathematical tractability. Glidden (2000)...

let $r$ be a commutative ring with identity and $m$ an $r$-module. in this paper, we associate a graph to $m$, say ${gamma}({}_{r}m)$, such that when $m=r$, ${gamma}({}_{r}m)$ coincide with the zero-divisor graph of $r$. many well-known results by d.f. anderson and p.s. livingston have been generalized for ${gamma}({}_{r}m)$. we show that ${gamma}({}_{r}m)$ is connected with ${diam}({gamma}({}_...

a graph $gamma$ is said to be vertex-transitive or edge‎- ‎transitive‎ ‎if the automorphism group of $gamma$ acts transitively on $v(gamma)$ or $e(gamma)$‎, ‎respectively‎. ‎let $gamma=cay(g,s)$ be a cayley graph on $g$ relative to $s$‎. ‎then, $gamma$ is said to be normal edge-transitive‎, ‎if $n_{aut(gamma)}(g)$ acts transitively on edges‎. ‎in this paper‎, ‎the eigenvalues of normal edge-tra...

let $gamma$ be a normal subgroup of the full automorphism group $aut(g)$ of a group $g$‎, ‎and assume that $inn(g)leq gamma$‎. ‎an endomorphism $sigma$ of $g$ is said to be {it $gamma$-central} if $sigma$ induces the the identity on the factor group $g/c_g(gamma)$‎. ‎clearly‎, ‎if $gamma=inn(g)$‎, ‎then a $gamma$-central endomorphism is a {it central} endomorphism‎. ‎in this article the conditi...

Abstract The Shanghai Laser Electron Gamma Source (SLEGS) is a powerful gamma source that provides MeV gamma-ray beams for nuclear science and technology. It was developed as one of the 16 beamline stations in Phase II Project Synchrotron Radiation Facility. slant-scattering mode first time systematically employed laser Compton scattering at SLEGS to produce energy-tunable quasi-monoenergetic b...

The synthesis of heavy, proton rich isotopes is a poorly understood astrophysical process. Thermonuclear (type Ia) supernova explosions are among the suggested sites and abundance some present in early solar system may be used to test models. 92Nb such an isotope one reactions playing role its 91Zr(p,gamma)92Nb. As no experimental cross sections were available for this reaction so far, nucleosy...

Laboratory animal models are an important part of test design. Certain conditions such as microbial contamination in diets of these models could affect the results of experiments. One of the most important routes that predispose to contamination is generated through feeding of laboratory animals. This study aimed to show the effect of gamma irradiation in reducing bacteria concentrations,...

CONTEXT A recently developed whole-blood interferon gamma (IFN-gamma) assay based on stimulation with the Mycobacterium tuberculosis-specific antigens early secreted antigenic target 6 and culture filtrate protein 10 shows promise for the diagnosis of latent tuberculosis (TB) infection. OBJECTIVE To compare the tuberculin skin test (TST) and the whole-blood IFN-gamma assay in the diagnosis of...