background: although the incidence of gastric cancer is declining during the last half century, this cancer still is the second morbid cancer in the world after lung cancer. the incidence of gastric cancer is 26 per 100,000 in iran. this study evaluated the effect of alpinia galangal on ags cells (human gastric adenocarcinoma epithelial cell line) and l929 cells (as a standard cell line origina...

helicobacter pylori was the main cause of gastric cancer (gc) in all over the world that results in intestinal- and diffuse-type carcinoma. infection by this bacterium remains chronic for a long time. in vitro studies have highlighted the role of stem cells in gc. h. pylori infection results in tissue injury and the adult/tissue stem cells subsequently start to replace the dead cells. the genet...

Objective HER-2/neu gene is overexpressed in diverse human cancers and studies suggest a role of its product – p185 protein – in tumor progression by specifically promoting the invasive capacity of tumor cells. Our aim was to evaluate HER-2/neu content in resectable gastric cancer in this geographical region and assess the relationship between p185 expression and clinicopathologic tumor paramet...

Background and objectives:  Gastric cancer is currently known as one of the most important causes of cancer-driven death all over the world. In patients with gastric cancer, a significant proportion of death occurs due to metastasis. On the other hand, down modulated E-cadherin level has been reported as an important contributor to tumor cell invasion and metastasis. In this re...

  Abstract   Background: Gastric cancer is the second most common cancer and also the second   cancer related death all over the world. In recent years recorded data for tumor   has shown a rise in the incidence of gastric cancer in young individuals. The present   study was designed to compare some of the epidemiologic characteristics of individuals   suffering from gastric cancer aged below a...

Background: Iran is an Eastern Mediterranean region country with the highest rate of gastric cancer. The present study aimed to evaluate the 5-year net survival of patients with gastric cancer in Iran using a relative survival framework.Methods: In a cross-sectional study, using life-table estimation of relative survival, we reported 1- to 5-year relative survival regarding age, sex, disease st...

the 5-year survival rate is a good prognostic indicator for patients with gastric cancer that is usually estimated based on kaplan-meier. in situations where censored observations are too many, this method produces biased estimations. this study aimed to compare estimations of kaplan-meier and weighted kaplan-meier as an alternative method to deal with the problem of heavy-censoring. data from ...

background: planning the educational programs and informing people regarding the prevention of widespread diseases like cancers is necessary. with regard to high mortality rate of gastric cancer, the present study was conducted to define the effect of education based on health belief model on knowledge, attitude and nutritional practice of homemakers. materials and methods: in this intervention...