the siberian sturgeon (acipenser baerii) is an economically important species. sturgeon stockassessment during fingerling production is considered to be one of the most difficult phases ofhatchery rearing. the present study investigated the expression of growth hormone (gh)mrna in unfertilized eggs, fertilized eggs, eyed eggs (2 day before hatching), non-viable eggsand newly-hatched siberian st...

aim : to evaluate the effect of active t. gondii tachyzoites and its products on the gene expression level of ifn-yr1 and ifn-yr2 in a murine model.   background : many studies have shown that the parasite toxoplasma gondii utilizes different mechanisms to inhibit the function of ifn-?, but the parasite effect on the function of ifn-yr1 and ifn-yr2 is still unclear. patients and methods : toxop...

introduction: calcium/calmodulin-dependent protein kinase ii (camkii) is highly expressed in the hippocampus, which has a pivotal role in reward-related memories and morphine dependence. methods: in the present study, morphine tolerance was induced in male wistar rats by 7 days repeated morphine injections once daily, and then gene expression profile of α-isoform of camkii (camkiiα) in the hipp...

Today, the use of oak as a replacement feed in poultry diets is well documented. However, oak contains polyphenol compounds (tannins) as antinutrient factors resulted in limited usage in the poultry rations. Generally, consumption of feeds containing tannin could affect gene expression level of immune system. Therefore, the aim of this study was to investigate the effect of different levels of ...

introduction: oxygen tension is one of the most important stimuli in stem cell biology. in this study, we investigate the considerable influence of hypoxia on cx43 gene expression as one of the most important gap junction on the surface of mesenchymal stem cells. methods: mesenchymal stem cells were isolated from c57bl/6 mouse bone marrow and cultured in dmem medium under low oxygen tension (1%...

Microarrays are one of the latest breakthroughs in experimental molecular biology, which allow monitoring of gene expression for tens of thousands of genes in parallel and are already producing huge amounts of valuable data. Analysis and handling of such data is becoming one of the major bottlenecks in the utilization of the technology. The raw microarray data are images, which have to be trans...

We present an interactive web tool for preprocessing microarray gene expression data. It analyses the data, suggests the most appropriate transformations and proceeds with them after user agreement. The normal preprocessing steps include scale transformations, management of missing values, replicate handling, flat pattern filtering and pattern standardization and they are required before perfor...

Micro-array data has enabled us to obtain an overview of the cell by measuring the expression levels of thousands of genes simultaneously. It has also opened the possibility for predicting possible cancerous cells accurately. Since these data sets are very large, we need to utilize machine learning techniques to analyse them efficiently. However, micro-array data also poses challenging problems...