The contributions of Sophya Kowalewski to the integrability theory of the equations for the heavy top extend to a larger class of Hamiltonian systems on Lie groups; this paper explains these extensions, and along the way reveals further geometric significance of her work in the theory of elliptic curves. Specifically, in this paper we shall be concerned with the solutions of the following diffe...

The precise mechanism(s) underlying the thermal hyperemic response to local heating of human skin are not fully understood. The purpose of this study was to investigate a potential role for H1 and H2 histamine-receptor activation in this response. Two groups of six subjects participated in two separate protocols and were instrumented with three microdialysis fibers on the ventral forearm. In bo...

As a follow-up to a recent paper considering two symmetric queues, the Shortest Queue First service discipline is presently analysed for two general asymmetric queues. Using the results previously established and assuming exponentially distributed service times, the bivariate Laplace transform of workloads in each queue is shown to depend on the solution M to a two-dimensional functional equati...

The substantia nigra pars reticulata (SNr) is a key basal ganglia output nucleus. Inhibitory outputs from SNr are encoded in spike frequency and pattern of the inhibitory SNr projection neurons. SNr output intensity and pattern are often abnormal in movement disorders of basal ganglia origin. In Parkinson's disease, histamine innervation and histamine H3 receptor expression in SNr may be increa...

The superior vestibular nucleus (SVN), which holds a key position in vestibulo-ocular reflexes and nystagmus, receives direct hypothalamic histaminergic innervations. By using rat brainstem slice preparations and extracellular unitary recordings, we investigated the effect of histamine on SVN neurons and the underlying receptor mechanisms. Bath application of histamine evoked an excitatory resp...

The aim of the present study was to investigate whether and by which mechanism; histamine can induce state-dependent retrieval of passive avoidance task. The pre-training or pre-test intracerebroventricular (i.c.v.) injection of histamine (20µg/mouse) impaired retrieval, when it was tested 24 h later. In the animals, which retrieval was impaired due to histamine pre-training administration, pre...

Calponins have been implicated in the regulation of actomyosin interactions in smooth muscle cells, cytoskeletal organisation in nonmuscle cells, and the control of neurite outgrowth. Domains homologous to the amino-terminal region of calponin have been identified in a variety of actin cross-linking proteins and signal transduction molecules, and by inference these 'calponin homology (CH) domai...

Definition. Let G and H be groups. Their direct product is the group G×H defined as follows. As a set G×H = {(g, h) : g ∈ G, h ∈ H} is just the usual Cartesian product of G and H (the set of ordered pairs where the first component lies in G and the second component lies in H). The group operation on G×H is defined by the formula (g1, h1)(g2, h2) = (g1g2, h1h2) for all g1, g2 ∈ G and h1, h2 ∈ H....

Most types of retinal neurons are spatially positioned in non-random patterns, termed retinal mosaics. Several developmental mechanisms are thought to be important in the formation of these mosaics. Most evidence to date suggests that homotypic constraints within a type of neuron are dominant, and that heterotypic interactions between different types of neuron are rare. In an analysis of macaqu...