BACKGROUND Blood transfusion is imperative when treating certain patients; however, it is not risk free. In addition to the possible transmission of contagious infectious diseases, incidents can occur immediately after transfusion and at a later time. AIMS This study aimed to examine the immediate transfusion incidents reported in a regional blood bank in the state of Minas Gerais between Dec...

The European spider Tegenaria agrestis (Walckenaer) (hobo spider) has been implicated as a spider of medical importance in the Pacific Northwest since its introduction in the late 1980s. Studies have indicated that the hobo spider causes necrotic tissue lesions through hemolytic venom or through the transfer of pathogenic bacteria introduced by its bite. Bacterial infections are often diagnosed...

BACKGROUND Non-ABO alloantibodies are frequently implicated in hemolytic transfusion reactions and are a leading cause of transfusion-related mortality. Detection of clinically significant non-ABO alloantibodies is reliant on an antibody screen, which is prone to clerical, technical, and reagent error. Data on the frequency of false-negative antibody screens due to the occurrence of these error...

CUTE acquired hemolytic anemia is uncommon, but dramatic in its clinical picture and often disastrous in its outcome. In 1940, Dameshek and Schwartz’ assembled about ioo cases reported in the literature since 1907, in which no definite etiology was evident. In addition, as cited by these authors, cases have been reported in which the anemia developed in association with definite or probable eti...

Photobacterium damselae subsp. damselae causes infections and fatal disease in marine animals and in humans. Highly hemolytic strains produce damselysin (Dly) and plasmid-encoded HlyA (HlyA(pl)). These hemolysins are encoded by plasmid pPHDD1 and contribute to hemolysis and virulence for fish and mice. In this study, we report that all the hemolytic strains produce a hitherto uncharacterized ch...

Microangiopathic hemolytic anemia occurs in a diverse group of disorders, including thrombotic thrombocytopenic purpura, hemolytic uremic syndrome, and prosthetic cardiac valves. Hemolytic anemia also occurs as a rare complication after mitral valve repair. In this report, we describe a case of microangiopathic hemolytic anemia following myxoma excision and mitral valve repair, which was presen...

Serological methods for the detection of antibody in the sera of tuberculous patients have been often tested, but the result has only ascertained that the complement fixation test has a supplementary dia gnostic value. In 1948, Middlebrook and Dubos1) proved a hemag glutination in tuberculous sera, using sheep erythrocytes sensitized with polysaccharide fraction of human tubercle bacilli (H37Rv...

A CUTE RENAL FAILURE is a well-known, though by no means inevitable, consequence of acute intravascular hemolytic transfusion reaction. The mechanism responsible for the renal damage is not fully understood, but undoubtedly depends on complex interrelationships of the plasma “free hemoglobin” concentration, the filtered load of hemoglobin, the per cent reabsorption of filtered water, urinary pH...

Some properties of the cell-free and cell-associated hemolysins of Escherichia coli were studied. Several strains of E. coli that were isolated from intestines of pigs with edema disease produce large quantities of cell-free hemolysin when grown in the presence of an extract of meat. The component of meat that stimulates production of cell-free hemolysin is not extracted by lipid solvents and i...

EACTIONS to the transfusion of blood are ordinarily classified as pyrogenic, allergic or hemolytic. The first two are relatively minor in importance, but hemolytic transfusion reactions, usually due to the use of incompatible blood, are severe and may be lethal. Another type of reaction to whole blood, not previously described, was observed by us in at least ii cases during the past three years...