Like rat C apolipoproteins, each of the C apolipoproteins from human blood plasma (C-I, C-11, C-111-1, and C111-2) bound to small chylomicrons from mesenteric lymph of estradiol-treated rats and inhibited their uptake by the isolated perfused rat liver. This inhibitory effect of the C apolipoproteins was independent of apolipoprotein E, which is present only in trace amounts in these chylomicro...

Citrobacter rodentium is the rodent equivalent of human enteropathogenic Escherichia coli infection. This study investigated regulation of hepatic and renal cytochrome P450 (P450) mRNAs, hepatic P450 proteins, cytokines, and acute phase proteins during C. rodentium infection. Female C3H/HeOuJ (HeOu) and C3H/HeJ (HeJ) mice [which lack functional toll-like receptor 4 (TLR4)] were infected with C....

background all conditions that interfere with blood flow at any level within the portal system can lead to portal hypertension. for better management of this disorder, it is important to determine the underlying cause. in previ­ous studies, extra-hepatic disorders have been reported as the main cause of portal hypertension in children. in this study, we investigate the under­lying causes of por...

conclusions capillaria hepatica should be considered in differential diagnoses in any child with fever, hepatomegaly, eosinophilia and hyperglobulinemia. case presentation the current paper reports a case of capillaria hepatica infection in a four-year-old boy which presented with fever, hepatomegaly, peripheral eosinophilia, and noticeable weight loss. the diagnosis was made on the histologica...

background the identification of the dorsal sector of the liver and its detailed vascular anatomy is of primary importance for surgical practice and segmental transcatheter arterial chemoembolization. objectives this study aimed to investigate the feeding arteries of tumors in dorsal sector of the liver. patients and methods computed tomography (ct) and digital subtraction angiography (dsa) ima...

coincidental occurrence of hepatocellular carcinoma (hcc) and cholangiocarcinoma, known as “collision tumors”, within a cirrhotic liver is rare. herein, we report a case of liver transplantation (lt) in a patient with such collision tumors. our patient was a 56-year-old woman with hepatitis c virus-related cirrhosis and 2 focal hepatic lesions, measuring 1.5 and 3 cm, in the liver segments 8 an...

objective(s):diabetes plays an important role in the induction of the liver injury. grape seed proanthocyanidin (gsp) have a wide range of medicinal properties against oxidative stress. in this study we evaluated antioxidant effects of gsp on liver in streptozotocin-induced diabetic rats. materials and methods: thirty male sprague–dawley rats were divided into three groups: control, untreated d...