conclusions our findings indicate that heterogeneity at +2109 locus of ifn-γ gene but not at +874 locus could interfere with successful therapy in patients infected with hcv genotype 1. results of 158 patients, 110 (69.5%) subjects achieved svr and 48 (30.5%) subjects did not respond to therapy. the frequency of aa genotype (p = 0.001; or: 11.2; ci: 2.26-63.21) and a allele (p = 0.01; or: 3.23;...

background: the use of devices emitted microwave radiation such as mobile phones, wireless fidelity (wi-fi) routers, etc. is increased rapidly. it has caused a great concern; the researchers should identify its effects on people's health. we evaluated the protective role of vitamin c on the metabolic and enzymatic activities of the liver after exposure to wi-fi routers. material and methods: 70...

Background: Acetaminophen overdose can result in hepatic injury, mainly through oxidative stress. Objective: We investigated the protective effect of Cuminum cyminum (C. cyminum) seed powder after acetaminophen administration. Methods: Thirty male rats were divided into five groups (n=6): Control group, Acetaminophen (A) group, and Acetaminophen + C. cyminum 200, 400, 800 mg/kg (A+C) groups. Af...

Objective(s): Liver transplantation is the most important therapy for end-stage liver disease and ischemia reperfusion (I/R) injury is indeed a risk factor for hepatic failure after grafting. The role of miRNAs in I/R is not completely understood. The aim of this study was to investigate the potential protective role of the mesenchymal stem cells (MSCs) and ischemic pr...

Objective: Effects of Commiphora mukul and Commiphora myrrha ethanolic extracts and Terminalia chebula<span style...

Hepatic calcification is usually associated with infectious, vascular, or neoplastic processes in the liver. We report the first case of beta-thalassemia major with isolated diffuse hepatic calcification in a 23 year old woman, who had been transfusion-dependent since the age of 6 months. She was referred to our center with a chief complaint of abdominal pain. Computed tomography scan of the ab...

Etiology of Physiologic Neonatal Hyperbili­rubinemia. Every newborn infant develop·s hyperbilirubinemia during the first week of life which is called "physiologic". There are several factors responsible for the development of physiologic hyperbilirubinemia, as follows:  1. Increased bilirubin production, due to a - Increased blood volume. b - Decreased R.B.C. survival time.  c - Increased in...

hepatic calcification is usually associated with infectious, vascular, or neoplastic processes in the liver. we report the first case of beta-thalassemia major with isolated diffuse hepatic calcification in a 23 year old woman, who had been transfusion-dependent since the age of 6 months. she was referred to our center with a chief complaint of abdominal pain. computed tomography scan of the ab...