Saeed Fotouhikia

Neonatal Research Center, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

[ 1 ] - Investigating the Association of Cord Blood Resistin and Birth Weight in Term and Preterm Neonates

BackgroundResistin is reported as an antagonistic hormone of insulin and in the literature. Nowadays, importance of resistin is being more highlighted in the metabolism of mother and fetus during pregnancy. This study aimed to assess the level of resistin in the umbilical cord and blood sugar at birth and evaluate the association of resistin and neonatal birth weight.Materials and MethodsThis c...

[ 2 ] - The protective effect of Zataria multiflora Boiss. hydroalcoholic extract on TNF-α production, oxidative stress, and insulin level in streptozotocin-induced diabetic rats

Objective: Oxidative stress leads to reactive oxygen species (ROS) overproduction, which causes tissue injury in diabetic patients. The aim of this study was to evaluate the effects of Zataria multiflora extract on TNF-α, oxidative stress products, and insulin levels as well as lipid profile in diabetic rats. Materials and Methods: Rats were randomly divided into 6 groups of 10 animals. Diabete...

[ 3 ] - Diffuse Hepatic Calcifications in a Transfusion-Dependent Patient with Beta-Thalassemia: A Case Report

Hepatic calcification is usually associated with infectious, vascular, or neoplastic processes in the liver. We report the first case of beta-thalassemia major with isolated diffuse hepatic calcification in a 23 year old woman, who had been transfusion-dependent since the age of 6 months. She was referred to our center with a chief complaint of abdominal pain. Computed tomography scan of the ab...

[ 4 ] - The effect of human wharton’s jelly-derived mesenchymal stem cells on MC4R, NPY, and LEPR gene expression levels in rats with streptozotocin-induced diabetes

Objective(s): Type 1 diabetes (T1D) is an autoimmune disease resulting from inflammatory destruction of islets β-cells. Nowadays, progress in cell therapy, especially mesenchymal stem cells (MSCs) proposes numerous potential remedies for T1D. We aimed to investigate the combination therapeutic effect of these cells with insulin and metformin on neuropeptide Y, melanoco...

[ 5 ] - Evaluation of serum FGF23 in patients with beta-thalassemia major compared to healthy population and its associated factors

Background: The role of phosphate hemostasis in development of thalassemia bone disease has not been extensively studied yet. Due to the lack of sufficient human studies about the changes of serum Fibroblast growth factor-23(FGF23) in patients with beta-thalassemia major as the first step of investigating the role of FGF23 in thalassemia bone disease, the present study aimed to investigate the ...