Background Nicotine, cotinine and cadmium are harmful components of cigarettes that have an effect on human reproductive function. Although the effects of cigarette smoke on male reproductive function is characterized in several articles its mechanism of action is still unknown. In the present study, we investigate the effect of nicotine, cotinine and cadmium on human sperm creatine kinase acti...

background: nicotine, cotinine and cadmium are harmful components of cigarettes that have an effect on human reproductive function. although the effects of cigarette smoke on male reproductive function is characterized in several articles its mechanism of action is still unknown. in the present study, we investigate the effect of nicotine, cotinine and cadmium on human sperm creatine kinase act...

SUZANNE BELINSON: Association of Reproductive History with Human Papillomavirus and Cervical Intraepithelial Neoplasia Severity (Under the direction of Katherine Hartmann) Our objective was to uncover potential links between Human Papillomavirus infection, common reproductive outcomes and high-grade cervical pre-cancer. We evaluated common reproductive risk factors, by varied stratifications of...

The human male is of relatively low fertility and thus may be at greater risk from reproductive toxicants than are males of the common laboratory animal model species. Lack of knowledge of the physiological differences that contribute to interspecies variation between man and animals can prevent the effective application of animal data to the assessment of human reproductive risk. Evaluation of...

Inter-individual variation in levels of sex hormones results from differences in genetic, developmental, and environmental factors. We tested a hypothesis that programming of the fetal neuroendocrine axis may predispose some women to produce higher levels of steroid hormones during their menstrual cycles as adults. One hundred forty-five regularly menstruating 24- to 36- year-old women collecte...

197 words): Animal experiments and some human studies indicate that PBDEs may adversely affect male reproductive function. We collected three serum samples from 27 healthy adult men at 6-month intervals in the FlaRE study and assessed associations between PBDE exposure and reproductive function tests using mixed effects regression models, adjusting for confounders. Geometric mean concentrations...

L-Ergothioneine is a naturally occurring histidine-derived betaine (CAS No: 497-30-3) synthesized by bacteria and fungi, and found ubiquitously in plants and animals. It is present in many human foodstuffs. We evaluated the potential reproductive toxicity of L-Ergothioneine in Sprague-Dawley rats. L-Ergothioneine was administered at concentrations of 0.1, 0.3 or 0.9% in diet to F0 males (for 10...

BACKGROUND Overall reproductive performance of dairy herds is monitored by various indicators. Most of them do not consider all eligible animals and do not consider different management strategies at farm level. This problem can be alleviated by measuring the proportion of pregnant cows by specific intervals after their calving date or after a fixed time period, such as the voluntary waiting pe...