background and aims: adenovector gene transfer induces inflammatory response that finally leads to vector removal from delivered site. the effect of hydrodynamic pre-injection on adenovector mediated liver inflammation remained elusive. materials and methods: different mice groups were pre-treated by hydrodynamic saline, dexamethasone or nothing prior to adeno-luciferase administration. their s...

Thermodynamic fluctuations are significant at microscopic scales even when hydrodynamic transport models (i.e., Navier-Stokes equations) are still accurate; a well-known example is Rayleigh scattering, which makes the sky blue. Interesting phenomena also appear in non-equilibrium systems, such as the enhancement of diffusion during mixing due to the correlation of velocity and concentration flu...

A wide spectrum of Peritrichous bacteria undergo considerable physiological changes when they are inoculated onto nutrition-rich surfaces and exhibit a rapid and collective migration denoted as swarming. Thereby, the length of such swarmer cells and their number of flagella increases substantially. In this article, we investigated the properties of individual E. coli-type swarmer cells confined...

We describe the results of three-dimensional (3D) numerical simulations designed to study turbulent convection in the stellar interiors, and compare them to stellar mixing-length theory (MLT). Simulations in 2D are significantly different from 3D, both in terms of flow morphology and velocity amplitude. Convective mixing regions are better predicted using a dynamic boundary condition based on t...

We present various numerical studies conducted with a novel pore-scale simulation technology called Direct Hydrodynamic (DHD) Simulation that can be used to study multiphase flow at various scales ranging from individual pore-scale events to complex scenarios like capillary de-saturation and relative permeability of digitized rock samples. DHD uses a diffuse interface description for fluid-flui...

Single-cell studies of phenotypic heterogeneity reveal more information about pathogenic processes than conventional bulk-cell analysis methods. By enabling high-resolution structural and functional imaging, a single-cell three-dimensional (3D) imaging system can be used to study basic biological processes and to diagnose diseases such as cancer at an early stage. One mechanism that such system...

In this paper, we show how with the grid middleware ObjectWeb ProActive, we have improved and adapted the deployment of a numerical Hydrodynamic Simulation application, the TELEMAC parallel System, for desktop grid. INTRODUCTION Two-dimensional mathematical models are increasingly used for the simulation of flood propagation in river plains. This type of model are now preferred to the former 1D...

incorporate hundreds of millions of semiconductor devices (transistors, diodes, optical devices, etc.). To predict the performance of the VLSI circuits, the current-voltage (I-V) characteristics of the semiconductor device are required. Semiconductor device simulation codes provide a way of predicting I-V curves as device parameters are varied, without having to fabricate the device first. (The...