BACKGROUND Elevated sodium excretion in urine resulting from excessive sodium intake can lead to hypercalciuria and contribute to the formation of urinary stones. The aim of this study was to evaluate salt intake in patients with urinary lithiasis and idiopathic hypercalciuria (IH). METHODS Between August 2007 and June 2008, 105 lithiasic patients were distributed into 2 groups: Group 1 (n = ...

OBJECTIVE Idiopathic hypercalciuria is characterised by renal stone formation and vertebral osteoporosis. The syndrome displays high clinical variability with patients almost equally distributed between fasting or renal type (prevalent calcium loss) and absorptive type (prevalent increase of intestinal absorption). Absorptive hypercalciuria (AH) is characterised by hypersensitivity of calcium-s...

Frick KK, Asplin JR, Krieger NS, Culbertson CD, Asplin DM, Bushinsky DA. 1,25(OH)2D3-enhanced hypercalciuria in genetic hypercalciuric stone-forming rats fed a low-calcium diet. Am J Physiol Renal Physiol 305: F1132–F1138, 2013. First published August 7, 2013; doi:10.1152/ajprenal.00296.2013.—The inbred genetic hypercalciuric stone-forming (GHS) rats exhibit many features of human idiopathic hy...

Gain-of-function mutations in the calcium ion-sensing receptor (CaR) cause hypocalcemia with low PTH levels. It is stated that patients with activating CaR mutations generally show milder degree of hypocalcemia before treatment and more profound hypercalciuria during treatment than those with idiopathic hypoparathyroidism (IHP). To test this validity we analyzed the data of serum and urinary ca...

background: previous studies have demonstrated that patients with insulin-dependent diabetes mellitus (iddm) have a high prevalence of osteopenia.  hypercalciuria has also been well documented in human diabetes and many children with insulin-dependent diabetes mellitus have short stature.   objective: to investigate the relationship of hypercalciuria and hyperphosphaturia with growth retardatio...

BACKGROUND AND OBJECTIVES Sodium thiosulfate (STS) reduced calcium stone formation in both humans and genetic hypercalciuric stone forming (GHS) rats. We sought to measure urine chemistry changes resulting from STS administration in people. DESIGN SETTING PARTICIPANTS MEASUREMENTS: STS was given to healthy and hypercalciuric stone forming adults. Five normal non-stone forming adults (mean age 3...

UNLABELLED Dent disease is a rare X-linked tubulopathy with low molecular weight proteinuria, hypercalciuria, nephrolithiasis, nephrocalcinosis and progressive renal failure. We describe the case of a 9-year-old boy who presented with nephrotic-range albuminuria at the age of 3 years. In the absence of a clear diagnosis, a renal biopsy was performed at 4 years, which revealed minimal change dis...

background wilson’s disease (wd) is a rare autosomal-recessive disorder characterized by a mutation in the atp7b gene, located on chromosome 13, which encodes a protein involved in the metabolism of copper. case presentation we described the case of an indian male with a history of polydipsia and polyuria, related to hypercalciuria and consequent nephrocalcinosis. the symptoms began at the age ...

Background: The application of extracorporeal shock wave lithotripsy (ESWL) to calcium oxalate dihydrate (COD) renal calculi gives excellent fragmentation results. Nevertheless, the retention of postESWL fragments within the kidney is still an important trouble. The aim of this paper is to study the regrowth of COD real spontaneously passed post-ESWL calculi fragments as a function of urinary c...